Protein Alignment CG7879 and Rbm12b

DIOPT Version :10

• Sequence 1: NP_647626.1
• Gene: CG7879 / 38184
• FlyBaseID: FBgn0035235
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001395740.1
• Gene: Rbm12b / 313069
• RGDID: 1307658
• Length: 843
• Species: Rattus norvegicus
• Alignment Length: 1117
• Identity: 225/1117 - (20%)
• Similarity: 365/1117 - (32%)
• Gaps: 406/1117 - (36%)

  Fly     1 MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLM 65
            |:|:||||.||:.|...|||:||.||:||:||||:|||:.|:|||.|:||||||.|:.:....:.
  Rat     1 MAVVIRLQGLPFIAGPVDIRHFFKGLTIPDGGVHVIGGKAGEAFIIFATDEDARRAISRSGGFIK 65

  Fly    66 EIQVRLLLSSRAEMQKVIETARKAASAQAPVSVPVPMPVVVPVTAAKVAGPAAPLPPIIGGLNTF 130
            :..|.|.|||:.||||.|:..|.|.                       .|...|.|
  Rat    66 DSSVELFLSSKVEMQKTIDMKRSAR-----------------------VGRGRPGP--------- 98

  Fly   131 LGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRKRR 195
                :..||  |.:..|:                                  |..:|.||
  Rat    99 ----EASGV--GNMYHFI----------------------------------DALKEEER----- 118

  Fly   196 SDRLDKSQERELKMVAGGGALPSPWAQPPQNQLPAVGLGLN-MGLNLNLPQIPSLQS-------- 251
                          .:|.|:..:|.|          |..:| .||:|...:...|::
  Rat   119 --------------YSGYGSAVNPDA----------GFHINGTGLDLRPRKTRPLKAENPYLFLR 159

  Fly   252 ---YTTSTTTTNV-------------------TNNYNLEPSATSVQLLTALQQVSS--GSAAPAQ 292
               |..:.....|                   .|...:...|:.|.....|:...|  ||.....
  Rat   160 GLPYLVNEDDVRVFFSGLCVDGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEV 224

  Fly   293 PSKSESEPIAFASV---------------NPYAQMYPQLFQQQQMLLQQQQTQAKVSPTMGGSPG 342
            ...||.:.|.|...               :|..::..:.|        .:::::|...|...||.
  Rat   225 MQGSEQQWIEFGGTASKGGDTLHKRSEEHSPSRRLNDRYF--------WKRSRSKSPRTRSRSPL 281

  Fly   343 GGSTPQVVADTCYIRMSGMCQNTSYSDIRKYFQGMYIPHNGIKIMMVNGSRTGVAYVEFSRVSSA 407
            |          .|:.:..:..:|:..|:|..|:...:.::.||.:..:..||..|:|.|......
  Rat   282 G----------FYVHLRNLSLHTNKRDLRYLFRDTDLSNDQIKFLYKDDRRTRYAFVMFKNQKDY 336

  Fly   408 QKAVQRNNTMFRDRLIQIVPVGDDEF-------------EMAEERASRQGQDGSRSHGNHNGGDR 459
            ..|:..:.|:.:.|.:.|.|:...|.             .:.|||..|..|..|         :.
  Rat   337 NTALGLHKTVLQYRPVLIDPISRKEMVKIIECYEKKRPESLEEERPGRVSQKYS---------EE 392

  Fly   460 GERGGGAPVPVPRPVTNVLYIEDLPQTTTEQDIMKMFSASYTVV--DILLSPSPKNRRESVAFVL 522
            |..|.|..:        .:||.:||...|:.::.|.| |.:::|  ||.|....|......|.|.
  Rat   393 GFPGSGQKL--------CIYIRNLPFDVTKGEVQKFF-ADFSLVEDDIYLLSDDKGIGLGEALVR 448

  Fly   523 FAREAEADSALQDTSKHYIGFRQLRVRSSSEEDMQN--------AKEKQRRANEQLLKEEA---- 575
            |..|.:|..|.:...:.::| .::.:|..|||.||.        :.||.:..:.....::.
  Rat   449 FKSEEQAMKAERLNRQRFLG-TEVLLRLISEEQMQEFGVNFSWMSNEKTQACSRSHDGDDCSCLF 512

  Fly   576 DQREELLKDQQRRQKQ----------------------QQQENENIQANRFAAD----PR----- 609
            |.::.|...|...|.:                      ||.:..:.:..|.:.:    ||
  Rat   513 DLKDPLATGQSFGQSESIRYQPKDFRKMGHFKHPRGYFQQSDRHSPEDFRHSPEDFGHPREEHSR 577

  Fly   610 -------RRQAED----------QQQQQQMNMGPNFNSNMSPNMMAPFVNGGNMPF--HMPPLQQ 655
                   ||..||          |.:::.....|      ..:...|:......|.  |.....|
  Rat   578 RSREEDWRRPLEDWKWPLEDDFRQSREKDCRQLP------EKDFRCPWEEDFRRPSQEHFRRSYQ 636

  Fly   656 NGVNNFPFNMNNNYNYNGNSNGNGP-----NYPNDNGGAGVIQRPRQEDVFVRVHNCEYATRAND 715
            ..:...|   :.::.|:...:....     .||.|..     .|..|||:     .|   ....|
  Rat   637 EHIRQPP---HEHFRYSREEDSRHVADEDFRYPADED-----FRTSQEDL-----RC---PTDED 685

  Fly   716 LGELFSLEHLRIEHIEQLFNERNQSSGEFIVEFSDPASCKLAIREFHNRRFRGRGLRVVAITPQE 780
            ..::...:|..:...:...:::.:..||.....||               |||.
  Rat   686 FRQVCLEDHREVPEGDLRRSDKFRLPGEDFWTSSD---------------FRGH----------- 724

  Fly   781 IADRMKKPFMDY--LPGGNGPRKAETNNANDGAGGNKASAQPSRRRGPSRFDKPQEQPSQQQDRP 843
                  .||:::  |.||                               :||..:.
  Rat   725 ------HPFVNFGHLEGG-------------------------------KFDFGKY--------- 743

  Fly   844 LSLEREDNSSTSSNAPVKQHFNPFARPDPPLSSSSLSPSNQGQVKPTSPVPVPTSIIPDKFNRPG 908
                   |..:.|.|.|....|             ||..:.|             |||
  Rat   744 -------NIGSFSEAKVTSDLN-------------LSCRSGG-------------IIP------- 768

  Fly   909 CVVAMRNVPFKAELKDIMRFFSDYKLSPDDIIRRFNDEGKPTGDTRVAFESPSEARSAFESRRKK 973
              |.:.|:||||...:|:.||..||:.|..:..::|::|.|.|:..||..:.:||.:|.:....:
  Rat   769 --VKISNLPFKANSNEILDFFHGYKVIPGSVSLQYNEQGLPIGEAIVAMTNYNEALAAVKDLSGR 831

  Fly   974 QIFNRTVYLDII 985
            .:..|.|.|.::
  Rat   832 PVGPRKVKLSLL 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:409932	39/72 (54%)
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:409699	15/69 (22%)
		RRM_SF	478..549	CDD:409669	20/72 (28%)
		RRM_SF	700..773	CDD:409669	10/72 (14%)
		RRM5_RBM12_like	909..983	CDD:409937	23/73 (32%)
Rbm12b	NP_001395740.1	RRM_SF	2..80	CDD:473069	42/77 (55%)
		RRM2_RBM12B	152..237	CDD:410140	13/84 (15%)
		RRM_SF	283..362	CDD:473069	17/78 (22%)
		RRM4_RBM12B	401..476	CDD:410142	21/84 (25%)
		PTZ00465	<619..703	CDD:185644	15/99 (15%)
		RRM_SF	767..843	CDD:473069	26/84 (31%)