Protein Alignment CG7879 and Rbm12b

DIOPT Version :9

• Sequence 1: NP_647626.1
• Gene: CG7879 / 38184
• FlyBaseID: FBgn0035235
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_006237956.2
• Gene: Rbm12b / 313069
• RGDID: 1307658
• Length: 843
• Species: Rattus norvegicus
• Alignment Length: 1116
• Identity: 225/1116 - (20%)
• Similarity: 367/1116 - (32%)
• Gaps: 404/1116 - (36%)

  Fly     1 MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLM 65
            |:|:||||.||:.|...|||:||.||:||:||||:|||:.|:|||.|:||||||.|:.:....:.
  Rat     1 MAVVIRLQGLPFIAGPVDIRHFFKGLTIPDGGVHVIGGKAGEAFIIFATDEDARRAISRSGGFIK 65

  Fly    66 EIQVRLLLSSRAEMQKVIETARKAASAQAPVSVPVPMPVVVPVTAAKVAGPAAPLPPIIGGLNTF 130
            :..|.|.|||:.||||.|:..|.|.                       .|...|.|
  Rat    66 DSSVELFLSSKVEMQKTIDMKRSAR-----------------------VGRGRPGP--------- 98

  Fly   131 LGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRKRR 195
                :..||  |.:..|:                                  |..:|.||
  Rat    99 ----EASGV--GNMYHFI----------------------------------DALKEEER----- 118

  Fly   196 SDRLDKSQERELKMVAGGGALPSPWAQPPQNQLPAVGLGLN-MGLNLNLPQIPSLQS-------- 251
                          .:|.|:..:|.|          |..:| .||:|...:...|::
  Rat   119 --------------YSGYGSAVNPDA----------GFHINGTGLDLRPRKTRPLKAENPYLFLR 159

  Fly   252 ---YTTSTTTTNV-------------------TNNYNLEPSATSVQLLTALQQVSS--GSAAPAQ 292
               |..:.....|                   .|...:...|:.|.....|:...|  ||.....
  Rat   160 GLPYLVNEDDVRVFFSGLCVDGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEV 224

  Fly   293 PSKSESEPIAFASV---------------NPYAQMYPQLFQQQQMLLQQQQTQAKVSPTMGGSPG 342
            ...||.:.|.|...               :|..::..:.|        .:::::|...|...||.
  Rat   225 MQGSEQQWIEFGGTASKGGDTLHKRSEEHSPSRRLNDRYF--------WKRSRSKSPRTRSRSPL 281

  Fly   343 GGSTPQVVADTCYIRMSGMCQNTSYSDIRKYFQGMYIPHNGIKIMMVNGSRTGVAYVEFSRVSSA 407
            |          .|:.:..:..:|:..|:|..|:...:.::.||.:..:..||..|:|.|......
  Rat   282 G----------FYVHLRNLSLHTNKRDLRYLFRDTDLSNDQIKFLYKDDRRTRYAFVMFKNQKDY 336

  Fly   408 QKAVQRNNTMFRDRLIQIVPVGDDEF-------------EMAEERASRQGQDGSRSHGNHNGGDR 459
            ..|:..:.|:.:.|.:.|.|:...|.             .:.|||..|..|..|         :.
  Rat   337 NTALGLHKTVLQYRPVLIDPISRKEMVKIIECYEKKRPESLEEERPGRVSQKYS---------EE 392

  Fly   460 GERGGGAPVPVPRPVTNVLYIEDLPQTTTEQDIMKMFSASYTVV--DILLSPSPKNRRESVAFVL 522
            |..|.|..:        .:||.:||...|:.::.|.| |.:::|  ||.|....|......|.|.
  Rat   393 GFPGSGQKL--------CIYIRNLPFDVTKGEVQKFF-ADFSLVEDDIYLLSDDKGIGLGEALVR 448

  Fly   523 FAREAEADSALQDTSKHYIGFRQLRVRSSSEEDMQN--------AKEKQRRANEQLLKEEA---- 575
            |..|.:|..|.:...:.::| .::.:|..|||.||.        :.||.:..:.....::.
  Rat   449 FKSEEQAMKAERLNRQRFLG-TEVLLRLISEEQMQEFGVNFSWMSNEKTQACSRSHDGDDCSCLF 512

  Fly   576 DQREELLKDQQRRQKQ----------------------QQQENENIQANRFAAD----PR----- 609
            |.::.|...|...|.:                      ||.:..:.:..|.:.:    ||
  Rat   513 DLKDPLATGQSFGQSESIRYQPKDFRKMGHFKHPRGYFQQSDRHSPEDFRHSPEDFGHPREEHSR 577

  Fly   610 -------RRQAED----------QQQQQQMNMGP--NFNSNMSPNMMAP----FVNGGNMPFHMP 651
                   ||..||          |.:::.....|  :|......:...|    |..........|
  Rat   578 RSREEDWRRPLEDWKWPLEDDFRQSREKDCRQLPEKDFRCPWEEDFRRPSQEHFRRSYQEHIRQP 642

  Fly   652 PLQQNGVNNFPFNMNNNYNYNGNSNGNGPNYPNDNGGAGVIQRPRQEDVFVRVHNCEYATRANDL 716
            |.:     :|.::...:..:..:.:.   .||.|..     .|..|||:     .|   ....|.
  Rat   643 PHE-----HFRYSREEDSRHVADEDF---RYPADED-----FRTSQEDL-----RC---PTDEDF 686

  Fly   717 GELFSLEHLRIEHIEQLFNERNQSSGEFIVEFSDPASCKLAIREFHNRRFRGRGLRVVAITPQEI 781
            .::...:|..:...:...:::.:..||.....||               |||.
  Rat   687 RQVCLEDHREVPEGDLRRSDKFRLPGEDFWTSSD---------------FRGH------------ 724

  Fly   782 ADRMKKPFMDY--LPGGNGPRKAETNNANDGAGGNKASAQPSRRRGPSRFDKPQEQPSQQQDRPL 844
                 .||:::  |.||                               :||..:.
  Rat   725 -----HPFVNFGHLEGG-------------------------------KFDFGKY---------- 743

  Fly   845 SLEREDNSSTSSNAPVKQHFNPFARPDPPLSSSSLSPSNQGQVKPTSPVPVPTSIIPDKFNRPGC 909
                  |..:.|.|.|....|             ||..:.|             |||
  Rat   744 ------NIGSFSEAKVTSDLN-------------LSCRSGG-------------IIP-------- 768

  Fly   910 VVAMRNVPFKAELKDIMRFFSDYKLSPDDIIRRFNDEGKPTGDTRVAFESPSEARSAFESRRKKQ 974
             |.:.|:||||...:|:.||..||:.|..:..::|::|.|.|:..||..:.:||.:|.:....:.
  Rat   769 -VKISNLPFKANSNEILDFFHGYKVIPGSVSLQYNEQGLPIGEAIVAMTNYNEALAAVKDLSGRP 832

  Fly   975 IFNRTVYLDII 985
            :..|.|.|.::
  Rat   833 VGPRKVKLSLL 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:240954	39/72 (54%)
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:240700	15/69 (22%)
		RRM	<364..551	CDD:223796	47/201 (23%)
		RRM_SF	478..549	CDD:240668	20/72 (28%)
		RRM_SF	702..773	CDD:240668	10/70 (14%)
		RRM_hnRNPH_ESRPs_RBM12_like	910..982	CDD:240700	23/71 (32%)
Rbm12b	XP_006237956.2	RRM_SF	2..80	CDD:418427	42/77 (55%)
		RRM2_RBM12B	152..237	CDD:410140	13/84 (15%)
		RRM_SF	283..362	CDD:418427	17/78 (22%)
		RRM	<367..581	CDD:223796	46/232 (20%)
		RRM4_RBM12B	401..476	CDD:410142	21/84 (25%)
		PTZ00465	<619..703	CDD:185644	15/104 (14%)
		RRM_SF	767..843	CDD:418427	26/84 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3648
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D132643at33208
OrthoFinder	1	1.000	-	-		FOG0001433
OrthoInspector	1	1.000	-	-		otm45026
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13976
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.160