DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7879 and Grsf1

DIOPT Version :9

Sequence 1:	NP_647626.1	Gene:	CG7879 / 38184	FlyBaseID:	FBgn0035235	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_001094360.1	Gene:	Grsf1 / 305256	RGDID:	1310858	Length:	479	Species:	Rattus norvegicus

Alignment Length:	489	Identity:	96/489 - (19%)
Similarity:	174/489 - (35%)	Gaps:	128/489 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 SATSVQLLTA--LQQVSSGSAAPAQPSKSESEPIAFASVNPYAQMYPQLFQQQQMLLQQQQTQAK 332
            :|.|...|.|  |.:..:.:|.||:....||:       ..|.:..|.|            .:.:
  Rat    90 AAASYSALRAPLLPRSLAAAAGPARGYCQESK-------TTYLEDLPPL------------PEYE 135

  Fly   333 VSPTMGGSPGGGSTPQVVADTCYIRMSGMCQNTSYSDIRKYFQGMYI--PHNGIKIMM-VNGSRT 394
            :||:..|        :.|.|...||..|:..:.:..|:..:|....|  ..|||..:: .:|.|.
  Rat   136 LSPSKLG--------EEVDDVYLIRAQGLPWSCTVEDVLSFFSDCRIRNSENGIHFLLNRDGKRR 192

  Fly   395 GVAYVEFSRVSSAQKAVQRNNTMFRDRLIQIVPVGDDEFEMAEERASRQGQDGSRSHGNHNGGDR 459
            |.|.:|.......|||::::......|.:::..:.:::.:...:....:
  Rat   193 GDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVK---------------- 241

  Fly   460 GERGGGAPVPVPRPVTNVLYIEDLPQTTTEQDIMKMFSASYTVVDILLSPSPKNRRES-VAFVLF 523
                     |.|.....|:.:..||.:..|:||:..| |...:|||......:.||:: .|:|.|
  Rat   242 ---------PTPALSDGVVRLRGLPYSCNEKDIVDFF-AGLNIVDITFVMDYRGRRKTGEAYVQF 296

  Fly   524 AREAEADSALQDTSKH--YIGFRQLRVRSSSEEDMQN--AKEKQRRANEQLLKEEADQREELLKD 584
            .....|:.||   .||  .||.|.:.:..|...:::.  ...|.::.......:...:.|.:.
  Rat   297 EEPEMANQAL---LKHREEIGNRYIEIFPSRRNEVRTHVGSHKGKKMVSSPTTKYITEPEVVF-- 356

  Fly   585 QQRRQKQQQQENENIQANRFAADPRRRQAEDQQQQQQMNMGPNFNSNMSPNMMAPFVNGGNMP-- 647
                  ::.:.||         |.|...|.:.:::.::      ...|| :.:|..|:.|.:|
  Rat   357 ------EEHEVNE---------DARPMTAFESEKEIEL------PKEMS-DKLAEAVDFGAVPSL 399

  Fly   648 --FHMP--PLQQNG---VNNF----PFNMNNNYNYNGNSNGNGPNYPNDNGGAGVIQRPRQEDVF 701
              .||.  |.|.|.   :|.|    |..:...|:.:|.:.|                   :.||.
  Rat   400 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATG-------------------EADVH 445

  Fly   702 VRVHNCEYATRANDLGELFSLEHLRIEHIEQLFN 735
            ...|....|....|      ..|::..:||...|
  Rat   446 FDTHEDAVAAMLKD------RSHVQHRYIELFLN 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:240954
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:240700	18/72 (25%)
		RRM	<364..551	CDD:223796	41/192 (21%)
		RRM_SF	478..549	CDD:240668	23/73 (32%)
		RRM_SF	702..773	CDD:240668	7/34 (21%)
		RRM_hnRNPH_ESRPs_RBM12_like	910..982	CDD:240700
Grsf1	NP_001094360.1	RRM1_GRSF1	148..226	CDD:241174	18/77 (23%)
		RRM2_GRSF1	248..321	CDD:240949	24/76 (32%)
		RRM	328..>458	CDD:223796	28/172 (16%)
		RRM3_GRSF1	400..474	CDD:241177	20/99 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910