Protein Alignment CG7879 and rbm12

DIOPT Version :10

• Sequence 1: NP_647626.1
• Gene: CG7879 / 38184
• FlyBaseID: FBgn0035235
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_012808099.1
• Gene: rbm12 / 100038118
• XenbaseID: XB-GENE-491733
• Length: 880
• Species: Xenopus tropicalis
• Alignment Length: 1102
• Identity: 235/1102 - (21%)
• Similarity: 375/1102 - (34%)
• Gaps: 341/1102 - (30%)

  Fly     1 MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLM 65
            |:|:||||.||..|...|||:|||||:||:|||||:|||:|:|||.|:||||||..|::....:.
 Frog     1 MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIK 65

  Fly    66 EIQVRLLLSSRAEMQKVIETARKAASAQAPVSVPVPMPVVVPVTAAK-VAGPAAPLPPIIGGLNT 129
            ..:|.|||||:.|||.:||.:|:.... |.|.:|       |..|.: |..|||.:     |..|
 Frog    66 GSKVSLLLSSKTEMQNMIELSRRRFET-ANVDLP-------PANAGRTVLTPAAGM-----GATT 117

  Fly   130 FLGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRKR 194
            .|.:..:    ..|||||......|..|::..
 Frog   118 VLSRVNL----PTTVPSFSGPSTSAVATVTST--------------------------------- 145

  Fly   195 RSDRLDKSQERELKMVAGGGALPSPWAQPPQNQLPAVGLGLNMGLNLNLPQIPSLQSYTTSTTTT 259
                ::.|:.......:|.|..|...:.|..||..:             ..:||..:..|:....
 Frog   146 ----IESSKNITTFSTSGVGTNPPTLSAPYGNQTYS-------------STVPSAPAPLTAVPPP 193

  Fly   260 NVTNNYNLEPSATSVQLLTALQQVSSGSAAPAQPSKSESEPIAFASVNPYAQMYPQLFQQQQMLL 324
            .:       |...::|.|..|..:.:....|..|......|:......|.....|.:.....|..
 Frog   194 PM-------PPMPTIQTLPPLPAIPTIPPMPVPPPVPTLPPVPPVPPIPPVPPVPSMAPLPPMSG 251

  Fly   325 QQQQTQAKVSPTMGGSPGGGST--------------------------PQVVADTCYIRMSGMCQ 363
            ........|.|...|..|.||:                          |.:..|..|:.:.|:..
 Frog   252 IPPMNPPPVGPIPAGMNGSGSSMSNNMNPLFLGPVNTIPLSSPNALKPPPLNHDDPYVCLHGLPV 316

  Fly   364 NTSYSDIRKYFQGMYIPHNGIKIMM-VNGSRTGVAYVEFSRVSSAQKAVQRNNTMFRDRLIQIVP 427
            ..|.:||:.:|.|:.|  :||.::. ..|...|.|.|:........:|::||..:...|.|::.|
 Frog   317 PVSEADIKDFFHGLRI--DGIVVLKDPMGRHNGSALVKLITPHDTFEALKRNRMLLGQRFIEVSP 379

  Fly   428 VGDDEF-----------------------EMAEERASRQGQDGSRSHGNHNGGDRGERGGGAPVP 469
            ..:.::                       ::.....|...|...||...|..|
 Frog   380 ATERQWMVSAGHILKPQNVGHHGPPPLMQQLITRSKSPSTQSRPRSRSPHEHG------------ 432

  Fly   470 VPRPVTNVLYIEDLPQTTTEQDIMKMFSASYTVVDILLSPSPKNRRESVAFVLFAREAEADSALQ 534
                  ..:|::.||.....:.::..|..    :||:         |...::.:....:|
 Frog   433 ------FCVYLKGLPYEAENKHVIDFFKK----LDIV---------EDSIYIAYGSNGKA----- 473

  Fly   535 DTSKHYIGFRQLRVRSSSEEDMQNA--KEKQRRANEQLLKEEADQREELLKDQQRRQKQQQQENE 597
             |.:.::.||       :|||.::|  :.||...|..:......::..|.|....|:|.|..
 Frog   474 -TGEGFLEFR-------NEEDYKSALCRHKQYMGNRFVQVHPITKKAMLEKIDMIRKKMQSY--- 527

  Fly   598 NIQANRFAADPRRRQAEDQQQQQQMNMGPNFNSNMSPNMMAPFVNGGNMPFHMPPLQQNGVNNFP 662
                                         |::.:....:.|.|...|
 Frog   528 -----------------------------NYSEHKDAPLDAEFEKHG------------------ 545

  Fly   663 FNMNNNYNYNGNSNGNGPNYPNDNGGAGVIQRPRQEDVFVRVHNCEYATRANDLGELFSLEHLRI 727
                                            ||   ::..:.|..|:....|:...|..|...|
 Frog   546 --------------------------------PR---LWGHLSNLPYSIMRKDISHFFISEGFAI 575

  Fly   728 EH--IEQLFNERNQSSGEFIVEFSDPASCKLAIREFHNRRFRGRGLRVVAITPQEIAD-RMKKPF 789
            :.  ::.|.:...|..|:.:|:|......:.:.| .|.::..||.:.:..:..:|..| .:..|
 Frog   576 DENFVQLLVDNNGQCIGQALVQFRSEDDARKSER-LHRKKLNGRDVFLHIVNSEERKDIELNPP- 638

  Fly   790 MDYLPGGNG--------PRKAETNN---ANDGAGGNKASAQ----PSRRRGPSRFDKPQEQP--- 836
               |.|..|        |...||.:   :..|:|....:..    |....||:.|..|...|
 Frog   639 ---LHGRRGSKMPVYVNPPSIETISDEFSFPGSGIKDVNGPNFNFPVNFPGPNNFGLPVPPPVIG 700

  Fly   837 -SQQQDRPLSLEREDNSSTSSNAPV-KQHF----NPFARPDPPLSSSSLSPSNQGQVKPTSPVPV 895
             :..:.||    .....:..|:||| .|.|    |.|:.|..|..|....|...|.
 Frog   701 STFVEPRP----PPPMPANVSSAPVDPQSFGSSPNSFSGPPSPFVSGGPPPFGSGP--------- 752

  Fly   896 PTSIIPDKFNR----------------------------PG----------CVVAMRNVPFKAEL 922
            |.:.||..||.                            ||          .|:.::|:||...:
 Frog   753 PNANIPPNFNTAPPNIGSGPAILNAPPGFGPGNLSVSGPPGFGAGAAKSGPTVIRVQNMPFTVTV 817

  Fly   923 KDIMRFFSDYKLSPDDIIRRFNDEGKPTGDTRVAFESPSEARSAFESRRKKQIFNRTVYLDI 984
            .:|:.||..|:|.|..:..:|:|:|.|||:..|||||..||.:|......:.|.:|.|.|.:
 Frog   818 DEILDFFYGYQLIPGSVCLKFSDKGMPTGEAMVAFESRDEAMAAVVDLNDRPIGSRKVKLTL 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:409932	42/72 (58%)
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:409699	19/70 (27%)
		RRM_SF	478..549	CDD:409669	11/70 (16%)
		RRM_SF	700..773	CDD:409669	15/74 (20%)
		RRM5_RBM12_like	909..983	CDD:409937	27/73 (37%)
rbm12	XP_012808099.1	RRM1_RBM12	1..92	CDD:241189	51/90 (57%)
		PHA03255	<98..>210	CDD:165513	31/184 (17%)
		RRM2_RBM12	306..380	CDD:410141	19/75 (25%)
		RRM3_RBM12	424..524	CDD:409934	25/143 (17%)
		RRM_SF	549..638	CDD:473069	17/89 (19%)
		RRM5_RBM12	803..878	CDD:410145	27/74 (36%)