| Sequence 1: | NP_647624.1 | Gene: | Pex10 / 38182 | FlyBaseID: | FBgn0035233 | Length: | 299 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_689480.2 | Gene: | RNF185 / 91445 | HGNCID: | 26783 | Length: | 192 | Species: | Homo sapiens |
| Alignment Length: | 57 | Identity: | 23/57 - (40%) |
|---|---|---|---|
| Similarity: | 37/57 - (64%) | Gaps: | 3/57 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 242 NTPQCILCLEPRSDSSLTPCGHIFCWSCLLEWLE---ERDECPLCRESLKKSQVILL 295 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pex10 | NP_647624.1 | Pex2_Pex12 | 20..>173 | CDD:398431 | |
| HRD1 | <183..>287 | CDD:227568 | 20/47 (43%) | ||
| RING-HC_PEX10 | 244..295 | CDD:438190 | 21/53 (40%) | ||
| RNF185 | NP_689480.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | ||
| Required for ubiquitin ligase activity and protection against ER stress-induced cell death. /evidence=ECO:0000269|PubMed:27485036 | 29..80 | 19/44 (43%) | |||
| RING-HC_RNF185 | 37..93 | CDD:438402 | 22/55 (40%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 90..123 | 1/2 (50%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||