Protein Alignment Pex10 and PEX10

DIOPT Version :9

• Sequence 1: NP_001261265.1
• Gene: Pex10 / 38182
• FlyBaseID: FBgn0035233
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_722540.1
• Gene: PEX10 / 5192
• HGNCID: 8851
• Length: 346
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 105/348 - (30%)
• Similarity: 160/348 - (45%)
• Gaps: 61/348 - (17%)

  Fly     6 ARARQPEIVRSVQKDARYTNELAEDLSDVLR-LTGPRNWIKYNQMCRLLAELSYHGFASANNLQT 69
            |.|..||::|:.|||..|...|.......|. |.|.|.|:::.:...||::::|.|..:....||
Human     4 AAASPPEVIRAAQKDEYYRGGLRSAAGGALHSLAGARKWLEWRKEVELLSDVAYFGLTTLAGYQT 68

  Fly    70 LGEEYTGIIQVDGNYKQIPSRL----LQLIAIVLEFGGDSLFQRLMQKLDTYVANNDEIRTEIKP 130
            |||||..|||||.:...:||.|    |..:..||.:..|.....|.|:|.....:...::..:.|
Human    69 LGEEYVSIIQVDPSRIHVPSSLRRGVLVTLHAVLPYLLDKALLPLEQELQADPDSGRPLQGSLGP 133

  Fly   131 ---------------------QLKKIIQR----LRQSPSYVKALHKSLFYLDASKYQLSKRTTGI 170
                                 |.::.:.|    |||..:.::.||.:.||:....|.|:||.|||
Human   134 GGRGCSGARRWMRHHTATLTEQQRRALLRAVFVLRQGLACLQRLHVAWFYIHGVFYHLAKRLTGI 198

  Fly   171 NYVLIRHWLQPE-----------------FSLYG--------YKILGVITFLQVSVSLAISGWDA 210
            .|..:|    |:                 .||.|        |::||||:.|.:.:|:.:..: .
Human   199 TYQALR----PDPLRVLMSVAPSALQLRVRSLPGEDLRARVSYRLLGVISLLHLVLSMGLQLY-G 258

  Fly   211 WREHKRQQLESIKQAGKNFLQRSSSTKDVDPNTPQCILCLEPRSDSSLTPCGHIFCWSCLLEWLE 275
            :|:.:|.:.|.....|.:..:.|...:.|..| |.|.||||.|...:.|||||:|||.|:..|..
Human   259 FRQRQRARKEWRLHRGLSHRRASLEERAVSRN-PLCTLCLEERRHPTATPCGHLFCWECITAWCS 322

  Fly   276 ERDECPLCRESLKKSQVILLQNY 298
            .:.|||||||.....::|.|::|
Human   323 SKAECPLCREKFPPQKLIYLRHY 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex10	NP_001261265.1	Pex2_Pex12	20..>173	CDD:282595	51/182 (28%)
		zf-RING_2	244..284	CDD:290367	21/39 (54%)
PEX10	NP_722540.1	Pex2_Pex12	18..263	CDD:282595	65/249 (26%)
		RING	293..334	CDD:238093	23/40 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149659
Domainoid	1	1.000	75	1.000	Domainoid score	I9105
eggNOG	1	0.900	-	-		E1_COG5574
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5671
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4307
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54217
OrthoDB	1	1.010	-	-		D1593722at2759
OrthoFinder	1	1.000	-	-		FOG0005524
OrthoInspector	1	1.000	-	-		oto89260
orthoMCL	1	0.900	-	-		OOG6_103665
Panther	1	1.100	-	-	LDO	PTHR23350
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	1	1.000	-	-		X4476
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800