Protein Alignment CG12099 and rnf10

DIOPT Version :10

• Sequence 1: NP_647623.1
• Gene: CG12099 / 38181
• FlyBaseID: FBgn0035232
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: NP_001116727.1
• Gene: rnf10 / 560444
• ZFINID: ZDB-GENE-030131-2969
• Length: 778
• Species: Danio rerio
• Alignment Length: 820
• Identity: 271/820 - (33%)
• Similarity: 373/820 - (45%)
• Gaps: 186/820 - (22%)

  Fly     3 SNNSSNSKKQPQSSHHG---KSSSAESQRKSSELHTNSNKQRHSRRR-------NQVPTPRNDQQ 57
            :||||::|..|:||..|   ..|.|::..|:     |...:|:||:|       ...|.||..|.
Zfish    23 NNNSSSTKIPPRSSSTGLNPTDSKAKTDGKN-----NGGSKRYSRKREPTFAKAESFPGPRRSQP 82

  Fly    58 QQPQQPAKLRPNVDKRPKARGFGGGYDFPSPRGQDGASGSSRLAYSATGYSRSGDFDHELNSVYT 122
            |:       ..|.||||..|| |.|.      .|.|.:|..|....|.  :|..:|    :....
Zfish    83 QK-------NKNFDKRPPQRG-GAGV------RQYGLAGGGRREEVAE--NRRAEF----SPAQF 127

  Fly   123 QGSKKQNLNHLLNFHCVPRELERGHHHQAQQHHGLSGRKQR-------YNKEQFLQANFQFVIRS 180
            .|.||.:|||||||...||   .||.......|...||:.:       :|||.|||||.|||:..
Zfish   128 AGPKKISLNHLLNFTFEPR---GGHFGSGGDGHSCWGRRNKWGHKHKPFNKELFLQANCQFVVSD 189

  Fly   181 GAKAQVN-GSPDALIDWSYIEQINIQTTEELQCPICLYPPVAAKLTRCGHAYCWPCLLHYLSLSD 244
            ....|.: ..||.|:||..::|:.|.:.|...|||||||||||.:|||||.|||||:|||||||:
Zfish   190 DQDYQAHFTDPDTLVDWDCVQQVRIYSHEVPSCPICLYPPVAAHMTRCGHIYCWPCMLHYLSLSE 254

  Fly   245 KTWRKCPICYDAIHAGDLKSCTIEQLRDLQVGEKITFQLMRRRKGSMYIENHVAGLGETIERFPF 309
            |:|.||||||:|:|:.||||....:.|....|..||..||||.|||:.          .:....:
Zfish   255 KSWSKCPICYEAVHSADLKSVVAMETRQYVSGNSITMCLMRREKGSLV----------ALPSSQW 309

  Fly   310 VSAGEEAK-------RYSKFLIAKRMDVAAIIERER----NELLAESDVSCPEDVFIQQALVMLQ 363
            |...|..:       .|||.|:|.|..|..::..||    .:|..|.|  .|:..|||.||:.||
Zfish   310 VKVEEPIQFGDVQFCSYSKLLLASRQQVLGLLAEERMALQTQLSQEKD--DPQACFIQSALLQLQ 372

  Fly   364 ERVEKL-------------GV--------EKPDPK--------------------EDEEETAPVL 387
            ||.|.|             ||        |:..|:                    :||.:.|...
Zfish   373 EREESLLKRRRRKTAGSVDGVDMRKLSLSEQSSPEVTVVNNLTNSKPILQYASAFDDEVQDAQEE 437

  Fly   388 CLETETKIDIEKSDDASISSG-------EASSSLSYSSNHNKYYYFYQSNDGQNIYLHPLNVKML 445
            .||..|...:.::.: .|..|       |.:...|.:::|..||||||:.|||.::|||:||:.|
Zfish   438 VLEEMTNPSVHEAPE-EIPDGDVEDLPVEETPQSSQTAHHGPYYYFYQAEDGQQMFLHPVNVRCL 501

  Fly   446 QACYGTLDLGPLLIEAQIVQMEQHSMDEEHRRKFTCLGHLPLTCQFSVVEVELQPPVVTGGILKL 510
            |..||:|:..|..|.|.:|:::..::.|:.||:...|.||||||:||:.|::||||:::...|..
Zfish   502 QRQYGSLENSPQTITANVVEIDGQTVTEDIRRRHRYLSHLPLTCEFSLCELDLQPPILSKETLDS 566

  Fly   511 FKEDILHRKKERQRRDREERKREQHINEINDRQMGKLIASAANLDLSSSHEFPTCGFEEALPAPS 575
            |.:||..||:.||::.|:|::||:.|....:|:.||.  ...::.|.:.|.||.          .
Zfish   567 FADDIEKRKRLRQKKVRDEKRREKRIEMEENRKQGKY--PEVHIGLENLHHFPA----------F 619

  Fly   576 GSVPMNISNQDPGSRYSSVTLG-------SPKQE--MWPTIGSNSPG------------------ 613
            ||.|.|    .|......|.||       ||..:  |:|.:..:||.
Zfish   620 GSPPQN----GPQLHLPEVLLGPPSPLSSSPSSDGVMFPNLSEHSPSLSVVGVEEDSHCMSFAQM 680

  Fly   614 --GGGAPLDVQVGAWGRSAPPPPRAVMVPRTSDEDFE------------QRSVGHWGLGELLVGA 664
              ||.|.:|    ...::.|......:.|..:|.|.|            |.|... .||:.| ..
Zfish   681 LKGGKARVD----TGPKTTPKKADMFLAPPAADSDGESDNSDRVPVPSFQNSFSQ-ALGQAL-SK 739

  Fly   665 LDQKKQKVGAAKSNGAAPAESKKQKKAKGKKMVPLFATGM 704
            ||...|....     |.|....|..|.|.||...||:|.|
Zfish   740 LDNGNQTPAP-----ALPISDDKGGKKKKKKQKLLFSTSM 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12099	NP_647623.1	RING-HC_RNF10	211..263	CDD:438198	39/51 (76%)
rnf10	NP_001116727.1	RING-HC_RNF10	220..273	CDD:438198	39/52 (75%)