Protein Alignment Pcyt2 and PCYT1B

DIOPT Version :10

• Sequence 1: NP_647622.1
• Gene: Pcyt2 / 38180
• FlyBaseID: FBgn0035231
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_004836.2
• Gene: PCYT1B / 9468
• HGNCID: 8755
• Length: 369
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 169/329 - (51%)
• Similarity: 217/329 - (65%)
• Gaps: 34/329 - (10%)

  Fly     8 DDES----PVSTAPATPTSPMEFKMLPLFMDFED------FSICQPAPFSYDDKAMLELERCDYT 62
            |.||    |.|.:...|:..||        :.|.      .::..||||:.:.....:...
Human     7 DAESETGIPKSLSNEPPSETME--------EIEHTCPQPRLTLTAPAPFADETNCQCQAPH---- 59

  Fly    63 QRITYHMARAG-KTTRRVRVYADGIYDLFHQGHARQLMQAKNVFPNVYLIVGVCNDELTLRMKGR 126
            :::|...||.| ...|.||||||||:||||.||||.|||||.:|||.||:||||:|:||.:.||.
Human    60 EKLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGF 124

  Fly   127 TVMNGFERYEAVRHCRYVDEIVPNAPWTLNEEFIEEHKIDFVAHDDIPYGAGGVNDIYAPLKAKG 191
            ||||..|||||:||||||||::.:|||||..||:|:|||||||||||||.:.|.:|:|..:|..|
Human   125 TVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAG 189

  Fly   192 MFVATERTEGVSTSDIVARIVKDYDVYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELK---- 252
            |||.|:||||:|||||:.|||:|||||.||||.|||:||||||||::||::|.||::|::|
Human   190 MFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVK 254

  Fly   253 ---TRGKRELTKVKV---DIITKWEEKSREFIDAFLLLFGRE-RLNTFWNESKGRIIQALSPPGS 310
               .|.|..:.:|:.   |:|.||||||||||..||.|||.: .....:.|...|::|||||..|
Human   255 NVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQS 319

  Fly   311 PNGS 314
            |..|
Human   320 PVSS 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt2	NP_647622.1	PLN02413	75..334	CDD:215229	152/251 (61%)
PCYT1B	NP_004836.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		6/19 (32%)
		PLN02413	72..314	CDD:215229	145/241 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..369		9/15 (60%)