DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcyt2 and CCT2

DIOPT Version :9

Sequence 1:	NP_647622.1	Gene:	Pcyt2 / 38180	FlyBaseID:	FBgn0035231	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_193249.5	Gene:	CCT2 / 827179	AraportID:	AT4G15130	Length:	304	Species:	Arabidopsis thaliana

Alignment Length:	303	Identity:	131/303 - (43%)
Similarity:	185/303 - (61%)	Gaps:	43/303 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 AGKTTRRVRVYADGIYDLFHQGHARQLMQAKNVFPNVYLIVGVCNDELTLRMKGRTVMNGFERYE 136
            :..:.|.||||||||:||||.||||.:.|||..|||.||:||.||||:|.:.||:|||...||||
plant    14 SSSSDRPVRVYADGIFDLFHFGHARAIEQAKKSFPNTYLLVGCCNDEITNKFKGKTVMTESERYE 78

  Fly   137 AVRHCRYVDEIVPNAPWTLNEEFIEEHKIDFVAHDDIPY----GAGGVNDIYAPLKAKGMFVATE 197
            ::|||::|||::|:|||.|..||:::||||:||||.:||    |||  ||:|..:|:.|.|..|:
plant    79 SLRHCKWVDEVIPDAPWVLTTEFLDKHKIDYVAHDALPYADTSGAG--NDVYEFVKSIGKFKETK 141

  Fly   198 RTEGVSTSDIVARIVKDYDVYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKTRGKRELTKV 262
            ||||:|||||:.||||||:.||.|||.||||.:||.||| .||:.|:..::.:|:.:.|.:..|:
plant   142 RTEGISTSDIIMRIVKDYNQYVLRNLDRGYSREELGVSF-EEKRLRVNMRLKKLQEKVKEQQEKI 205

  Fly   263 KVDIIT------KWEEKSREFIDAFLLLFG--------------RERLNTFWNESKGRIIQALSP 307
            :....|      :|.|.:..::..||.:|.              ::||....:|...|::|
plant   206 QTVAKTAGMHHDEWLENADRWVAGFLEMFEEGCHKMGTAIRDGIQQRLMRQESEENRRLLQ---- 266

  Fly   308 PGSPNGSVNGDDPDATDDLDSEDEYMELPPDYGSGSCVSLSRK 350
                    ||    .|...|::||.|....::....||::|.|
plant   267 --------NG----LTISKDNDDEQMSDDNEFAEEDCVNVSNK 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt2	NP_647622.1	PLN02413	75..334	CDD:215229	126/282 (45%)
Pcyt2	NP_647622.1	CCT	77..226	CDD:173925	94/152 (62%)
CCT2	NP_193249.5	PLN02413	19..282	CDD:215229	127/281 (45%)
CCT2	NP_193249.5	CCT	19..170	CDD:173925	94/152 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1110
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I1093
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172502at2759
OrthoFinder	1	1.000	-	-		FOG0001344
OrthoInspector	1	1.000	-	-		mtm1135
orthoMCL	1	0.900	-	-		OOG6_101770
Panther	1	1.100	-	-	O	PTHR10739
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X834
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.920