DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcyt2 and SPCC1827.02c

DIOPT Version :9

Sequence 1:	NP_647622.1	Gene:	Pcyt2 / 38180	FlyBaseID:	FBgn0035231	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_588548.2	Gene:	SPCC1827.02c / 2539176	PomBaseID:	SPCC1827.02c	Length:	362	Species:	Schizosaccharomyces pombe

Alignment Length:	324	Identity:	142/324 - (43%)
Similarity:	184/324 - (56%)	Gaps:	57/324 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KEDD--ESPVSTAP--ATPTSPMEFKMLPLFMDFEDFSICQPAPFSYDDKAMLELERCDYTQRIT 66
            ||||  |||..:..  :...||:|.:  |..:.|::.|    .||||......|
pombe    51 KEDDKEESPSKSLEEISQSVSPVEEE--PRDVRFKELS----TPFSYPINDPPE----------- 98

  Fly    67 YHMARAGKTTRRVRVYADGIYDLFHQGHARQLMQAKNVFPNVYLIVGVCNDELTLRMKGRTVMNG 131
                     .|.|||||||::||||.||.|||.|||.|||||:||||:.||:||.|:||.||||.
pombe    99 ---------GRPVRVYADGVFDLFHIGHMRQLEQAKKVFPNVHLIVGLPNDQLTHRLKGLTVMND 154

  Fly   132 FERYEAVRHCRYVDEIVPNAPWTLNEEFIEEHKIDFVAHDDIPYGAGGVNDIYAPLKAKGMFVAT 196
            .||.||:|||::|||::.||||.:..||:|||||||||||||||.:....|||.|:|..|.|:.|
pombe   155 KERAEALRHCKWVDEVLENAPWVITPEFLEEHKIDFVAHDDIPYASDDSGDIYLPVKKVGKFIPT 219

  Fly   197 ERTEGVSTSDIVARIVKDYDVYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKTRGKRELTK 261
            :|||||||||::.||::|||.||.||||||.:.||||||...:.:..|::.:            |
pombe   220 KRTEGVSTSDLITRIIRDYDQYVMRNLARGVNRKELNVSLFKKNELDLRHHI------------K 272

  Fly   262 VKVDII-TKWEEKSREF---IDAFLLLFGRERLNTFWNESKGRIIQALSPPGSPN-----GSVN 316
            |..|.: ..|...:|:.   |.:||.:     ..|.:...|.. :...|.|.||.     |.:|
pombe   273 VLRDTLRNHWVSTTRDLKADIKSFLSM-----ATTDYQLQKNP-LHGSSEPSSPGPTGFLGGIN 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt2	NP_647622.1	PLN02413	75..334	CDD:215229	124/251 (49%)
Pcyt2	NP_647622.1	CCT	77..226	CDD:173925	99/148 (67%)
SPCC1827.02c	NP_588548.2	CCT	100..249	CDD:173925	99/148 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	186	1.000	Domainoid score	I764
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001344
OrthoInspector	1	1.000	-	-		otm47191
orthoMCL	1	0.900	-	-		OOG6_101770
Panther	1	1.100	-	-	LDO	PTHR10739
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R892
SonicParanoid	1	1.000	-	-		X834
TreeFam	1	0.960	-	-
	11	10.800