DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcyt2 and pcyt-1

DIOPT Version :9

Sequence 1:	NP_647622.1	Gene:	Pcyt2 / 38180	FlyBaseID:	FBgn0035231	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001033539.1	Gene:	pcyt-1 / 181021	WormBaseID:	WBGene00017241	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	384	Identity:	170/384 - (44%)
Similarity:	224/384 - (58%)	Gaps:	58/384 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PKEDDESPVSTAPATPTSPMEFKMLPLFMDFEDFSICQPAPFSYDDKAMLELERCDYTQRITYHM 69
            |:|:|......|     :.:|:.:..|..|       :|||||.:..|:...|..||:::||..|
Worm    19 PQEEDVEVKKKA-----TEVEYVVRSLASD-------EPAPFSDEALAITTREAVDYSKKITLAM 71

  Fly    70 ARAGKTTRRVRVYADGIYDLFHQGHARQLMQAKNVFPNVYLIVGVCNDELTLRMKGRTVMNGFER 134
            |.|.:..|.||:||||||||||.|||.||.|.|.:|||||||||||.|..|.:.|||||.:..||
Worm    72 AEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEER 136

  Fly   135 YEAVRHCRYVDEIVPNAPWTLNEEFIEEHKIDFVAHDDIPYGAGGVNDIYAPLKAKGMFVATERT 199
            |:.|||||||||:...|||....||::..|:||:|||.|||.|.|..|:|...:.:|||:.||||
Worm   137 YDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERT 201

  Fly   200 EGVSTSDIVARIVKDYDVYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKTRGKRELTKVKV 264
            |||||||:|.||::|||.||||||.||||.|||||.||:..|:::|||:|.||::|        :
Worm   202 EGVSTSDVVCRIIRDYDKYVRRNLQRGYSPKELNVGFLAASKYQIQNKVDSLKSKG--------I 258

  Fly   265 DIITKWEEKS----REFIDAFLLLFGRERLNTFWNESKGRIIQALSPPGSPN-GSVNGDDPD-AT 323
            ::::.|:.||    |:|||.|....|   ||.|....||.:..:.||..||: ||..|.:.. .|
Worm   259 ELLSTWKSKSDDIIRDFIDTFHKDGG---LNAFGGRLKGIMSMSRSPSPSPHEGSPTGIEHHLET 320

  Fly   324 DDLDSEDEYMELPPDYGSGSCVSLSRKQKRPDKVNASANLNYSEQP--EHKDVVDERRS 380
            .|.:.|:|.:|                   .:||        .||.  |.|:||.:|.|
Worm   321 QDEEEEEEALE-------------------EEKV--------VEQKIVEKKEVVKKRSS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt2	NP_647622.1	PLN02413	75..334	CDD:215229	138/264 (52%)
Pcyt2	NP_647622.1	CCT	77..226	CDD:173925	94/148 (64%)
pcyt-1	NP_001033539.1	CCT	79..228	CDD:173925	94/148 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158905
Domainoid	1	1.000	181	1.000	Domainoid score	I2064
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3680
Inparanoid	1	1.050	300	1.000	Inparanoid score	I1628
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29101
OrthoDB	1	1.010	-	-		D1172502at2759
OrthoFinder	1	1.000	-	-		FOG0001344
OrthoInspector	1	1.000	-	-		mtm4758
orthoMCL	1	0.900	-	-		OOG6_101770
Panther	1	1.100	-	-	O	PTHR10739
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R892
SonicParanoid	1	1.000	-	-		X834
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940