DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcyt2 and pcyt1a

DIOPT Version :9

Sequence 1:	NP_647622.1	Gene:	Pcyt2 / 38180	FlyBaseID:	FBgn0035231	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	XP_002934091.3	Gene:	pcyt1a / 100496938	XenbaseID:	XB-GENE-1001244	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	168/313 - (53%)
Similarity:	223/313 - (71%)	Gaps:	16/313 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ATPTSPMEFKMLPLFMDFEDFSICQPAPFSYDDKAMLELERCDYTQRITYHMARAGKTTRR-VRV 81
            |.|....:...:|:.:......:.:|||||.:    |:::|.:..:|::...|:.|....| |||
Frog    52 AGPNGTTDEDHVPIKVARHTMGVREPAPFSDE----LKVDRSNTYRRVSMEEAKLGTPIERPVRV 112

  Fly    82 YADGIYDLFHQGHARQLMQAKNVFPNVYLIVGVCNDELTLRMKGRTVMNGFERYEAVRHCRYVDE 146
            |||||:||||.||||.||||||:|||.:||||||:||||..:||.||||..|||:||:|||||||
Frog   113 YADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDELTHNLKGFTVMNEAERYDAVQHCRYVDE 177

  Fly   147 IVPNAPWTLNEEFIEEHKIDFVAHDDIPYGAGGVNDIYAPLKAKGMFVATERTEGVSTSDIVARI 211
            :|.||||||:.||:|:|:|||||||||||.:.|.:|:|..:|..|||..|:||||:|||||:.||
Frog   178 VVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRI 242

  Fly   212 VKDYDVYVRRNLARGYSAKELNVSFLSEKKFRLQNKMDELKTRGK----------RELTKVKVDI 266
            |:||||||||||.|||:||||||||::||:|.||.::|::|.:.|          :::.:..:|:
Frog   243 VRDYDVYVRRNLQRGYTAKELNVSFINEKRFNLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDM 307

  Fly   267 ITKWEEKSREFIDAFLLLFGRE-RLNTFWNESKGRIIQALSPPGSPNGSVNGD 318
            |.||||||||||..||.:||.| .|.....|.|||::||:||..||:.|...|
Frog   308 IQKWEEKSREFIGNFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTRD 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt2	NP_647622.1	PLN02413	75..334	CDD:215229	155/256 (61%)
Pcyt2	NP_647622.1	CCT	77..226	CDD:173925	106/149 (71%)
pcyt1a	XP_002934091.3	CCT	108..257	CDD:173925	106/148 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2893
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3680
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2365
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172502at2759
OrthoFinder	1	1.000	-	-		FOG0001344
OrthoInspector	1	1.000	-	-		mtm9481
Panther	1	1.100	-	-	LDO	PTHR10739
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R892
SonicParanoid	1	1.000	-	-		X834
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100