Protein Alignment pns and dennd4b

DIOPT Version :9

• Sequence 1: NP_647620.1
• Gene: pns / 38178
• FlyBaseID: FBgn0035229
• Length: 1449
• Species: Drosophila melanogaster
• Sequence 2: XP_031746823.1
• Gene: dennd4b / 100125065
• XenbaseID: XB-GENE-5886552
• Length: 1503
• Species: Xenopus tropicalis
• Alignment Length: 1063
• Identity: 205/1063 - (19%)
• Similarity: 335/1063 - (31%)
• Gaps: 388/1063 - (36%)

  Fly    17 LSSGSGNGSGNGSGPNIQVAPSSTLVQSPTSPGEQSQSQSE---LNQLKRDADPQ-FSRFADYFV 77
            ||||         ||..|.| .....::|.|.|..|....:   :|..|.::.|. |.|
 Frog   125 LSSG---------GPGNQRA-FLMFKRAPESMGLNSLGVMDICIINPSKGESTPNTFCR------ 173

  Fly    78 ICGLDLDTGLEPDRFAGDNLHCSPLDRA------YKSKPLAHYP----ENVPWNPFDAHGICMLS 132
                 :|..|....|......|.....|      |::..|:.:|    |..|....    :....
 Frog   174 -----VDRNLNTSMFGPALFLCYKKGTAKTHSLVYEAGVLSRFPSADSETFPLPEM----VATFC 229

  Fly   133 LPQGLR-----FRTQKHCIEPRFHSFATTREDGKRCYGFSLVFYEEIRNRNICGAIHTLQSMFIT 192
            ||.|..     ..|:.|.  |.|.:|..|...|::.||.::.|:|:...    |.:...|:
 Frog   230 LPMGATIESWPINTKYHM--PVFSTFVLTGASGEKVYGAAIQFHEQYPR----GCLSEKQN---- 284

  Fly   193 ELSNGQQTHSLSRVKQDGPVSRSLPRHFKVAGQAPQSAQSYYDINKDKLYVAKSITLICQAPYAF 257
                  |:..|..|....||:                       || .:...|||.::...|:..
 Frog   285 ------QSLGLLSVVDKRPVT-----------------------NK-SVQTKKSICVLSHWPFFD 319

  Fly   258 AAQMFLKNLYRCLPRQPGAGISLESYVYNILYEVMLPQPGK-SIRVYLPPTEPHLPPIALILQRP 321
            ..|.||..:||.....|.. :.:|.::.|.::.|..|.|.: .|.|.:.|.:      .::|.:|
 Frog   320 VFQKFLTFIYRYSISGPHV-LPIEKHISNFMFNVPFPSPQRPRILVQMSPYD------NVLLCQP 377

  Fly   322 LLATELPLLDFPLRLLFKYLGVECVIQLLTCVLLENQVLLRSTDYQRLMIVGECITSLLFPFVWP 386
             :::.|||.......|.:.||.|..:.||..||.|:::|:.|.....|..|||.:.|::||..|.
 Frog   378 -VSSPLPLSGASYVTLLQNLGPETAVTLLLAVLTEHKLLIHSQRPDVLTSVGEALVSIIFPLRWQ 441

  Fly   387 HVYAPILPAALHHFLDAPVPFVMGLHAECEAAHKIGSEATLCFVDIDKKHIQLPEELPVFPHKVD 451
            ..|.|:.|..|...|.|||||::|:|:.....|. ..:..|| ||:|...:...||..|
 Frog   442 CPYIPLCPLTLSDVLCAPVPFIVGIHSSYFDLHD-PPQDVLC-VDLDTNTLFQSEEKKV------ 498

  Fly   452 FMAEIGSVLDKFEIERDRDQEPSFRNGYVGRGAGGGVSGSGSSGSGGVDAMISSCTLPTGLQAAR 516
                                 ||.|                              :||
 Frog   499 ---------------------PSVR------------------------------SLP------- 505

  Fly   517 RSKERFQQMQETVYTLSGSPGGGVVDYQPLIAHPSRIDHVPRIADFLRRKGGIRGAGSPVGSPTV 581
                     ::....|.|:                 :..:.:..|.:..|        |:...|:
 Frog   506 ---------RKPCKVLLGT-----------------LSDLHKQLDEMYNK--------PMEEATL 536

  Fly   582 SLSSSPVGIYHDVDAVDATMPVSTRRAEKQKLSPVDQYYQDLRINNSVREIFLNRFVHMFHAYEY 646
            ..      :..|.|.:                     |.:..::...||..||.....:...|..
 Frog   537 EF------LLKDYDLI---------------------YGRRTQLELDVRAAFLRFMACLLKGYRS 574

  Fly   647 FVIYPNQARDEWISNRETLQNFDKSSFLSDQPEHHRAFLSRFLESQMFATLIDNKILAMWESQPD 711
            |::...||..|  ..|::...|:...|...:...|:.|.|:.|::|||...|::   ..:.|...
 Frog   575 FLLPITQAPSE--RTRDSSNLFNVEGFRKSRDRAHQKFYSQMLKTQMFTQFIED---CSFVSDRH 634

  Fly   712 EQLQLFD---QRVKLLRRRHGENMIAATSYEPCVLSQDSQQGFEKRLNCIDIEVTPPSE----IL 769
            ..|:..|   ::|::    .||.|                    :.|:.::::.:..||    |:
 Frog   635 ACLEFLDNCIEKVQI----DGEKM--------------------EDLHLVELDESHRSEHTVFIM 675

  Fly   770 ANR-----------AAY-FRSFPLLEKGVLNQECASRGNSLRRVKNGNKWRAREISLD------- 815
            ...           |.| :.|||:|                       ||...::..|
 Frog   676 PAEEPHEPGSGELPAQYMYESFPVL-----------------------KWELFDLPQDLLMAPPN 717

  Fly   816 ----QKPGSNAINRLSANLTTA-------DVSPALIAQ-------ANW-----TFVERLLKDIKS 857
                ..|.|.|..|....:..|       ...|.:.|:       ..|     |||......:::
 Frog   718 QSKSSAPSSPAPRRTKQEIKMAQRVAQKYSAMPDMWAKCLLGHCYGLWFIYLPTFVRATPSKVRA 782

  Fly   858 -KTKRMLLEKMGNEAVAL-------------GLKGDGIEENTLIASM--CDLLEKIWSHGLQNKQ 906
             :|....|::|.|:.|.|             |..|:.:....::..|  ..::..|.::|..||.
 Frog   783 LQTAYDALKQMENKKVVLPDEVCYRVLMQLCGQYGEPVLAVRVMLEMKKAGIVPNIITYGYYNKA 847

  Fly   907 GKSALWAHLQAYLEMQEARGAGDSSGTEQTPPVSSSPGGKMTIATASPALAWNAMR--------- 962
            ...:.|.                          |||..|:         |.|..:|
 Frog   848 ILESKWP--------------------------SSSQSGR---------LRWAKLRNVVLGAAQF 877

  Fly   963 -------KRMDYLSTFQTDFDSP 978
                   :|...||..||:...|
 Frog   878 RQPLKRKRRQAGLSLSQTESHLP 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pns	NP_647620.1	uDENN	70..171	CDD:214824	23/115 (20%)
		DENN	243..435	CDD:214823	60/192 (31%)
		dDENN	626..701	CDD:129037	20/74 (27%)
		RUN	<989..1083	CDD:295434
		PLAT_RAB6IP1	1095..1203	CDD:238855
		RUN	1376..1436	CDD:214736
dennd4b	XP_031746823.1	uDENN	207..268	CDD:397495	16/66 (24%)
		DENN	307..488	CDD:396629	60/190 (32%)
		dDENN	557..627	CDD:129037	20/74 (27%)
		PPR_2	801..841	CDD:404055	4/39 (10%)
		PPR repeat	803..832	CDD:276811	3/28 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000