Protein Alignment CG12091 and PPM1A

DIOPT Version :9

• Sequence 1: NP_001261261.1
• Gene: CG12091 / 38177
• FlyBaseID: FBgn0035228
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: XP_016876870.1
• Gene: PPM1A / 5494
• HGNCID: 9275
• Length: 459
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 84/412 - (20%)
• Similarity: 133/412 - (32%)
• Gaps: 138/412 - (33%)

  Fly    17 RSSFSTLLETATGGGSGAAAKGATKSGATPG--------------SSGA--PRPRFVSVVCGFAK 65
            |.:|..:|..|...|.....|  |||..:.|              ..||  .:|:       ..|
Human    34 RLNFFCVLGCAPSAGKTPVNK--TKSPCSHGVYSHYSKVYLEDQDIMGAFLDKPK-------MEK 89

  Fly    66 DNLRHKYKPGKYGEDS---W-FKASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTCERLVQC 126
            .|.:.:....:||..|   | .:...|...|:|:..|:..|..:.:..|...|.:.:.|     |
Human    90 HNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYC-----C 149

  Fly   127 SHF-----------------------NPQRPVNLLAYSYCELMEQKK---PILGSSTACVLILNR 165
            .|.                       |..|...|....:..:|.:||   ...||:...|||
Human   150 EHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLI--- 211

  Fly   166 ETSTVHT--ANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLP-------------------- 208
              |..||  .|.|||..::.|..:|        |:|....:.|.|
Human   212 --SPQHTYFINCGDSRGLLCRNRKV--------HFFTQDHKPSNPLEKERIQNAGGSVMIQRVNG 266

  Fly   209 ---------------PPGHGP--NVLSDSPESADTMSFPVRDGDVILIATDGVFD---------- 246
                           ..|.||  .::|..||..| :.....|...|::|.||::|
Human   267 SLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHD-IERSEEDDQFIILACDGIWDVMGNEELCDF 330

  Fly   247 -----NVPEDLMLQVLSEV------EGERDPVKLQMTA--NSLALMARTLSLNSEFLSPFALSAR 298
                 .|.:||. :|.:||      :|.||.:.:.:..  |:..:....:...:| |..:.....
Human   331 VRSRLEVTDDLE-KVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAE-LDKYLECRV 393

  Fly   299 RNNIQARGGKPDDITVVLATVA 320
            ...|:.:|....|:..|:.|:|
Human   394 EEIIKKQGEGVPDLVHVMRTLA 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12091	NP_001261261.1	PP2Cc	76..316	CDD:294085	66/331 (20%)
PPM1A	XP_016876870.1	PP2Cc	100..368	CDD:238083	60/287 (21%)
		PP2C_C	362..437	CDD:285117	9/55 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900