DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12091 and pptc7a

DIOPT Version :9

Sequence 1:	NP_001261261.1	Gene:	CG12091 / 38177	FlyBaseID:	FBgn0035228	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001007379.1	Gene:	pptc7a / 492506	ZFINID:	ZDB-GENE-041114-74	Length:	297	Species:	Danio rerio

Alignment Length:	265	Identity:	146/265 - (55%)
Similarity:	193/265 - (72%)	Gaps:	2/265 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 VSVVCGFAKDNLRHKYKPGK-YGEDSWFKASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTC 120
            ||...||.||..:...|.|. ||:|:.|.|...||||:||||||||||.||:||.:||..|||||
Zfish    30 VSASFGFGKDFRKGILKKGMCYGDDACFIARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTC 94

  Fly   121 ERLVQCSHFNPQRPVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVRE 185
            ||||:...|.|..||.:|..||.||::.|.|:|||||||:::|:|::..:||||:|||||:|||.
Zfish    95 ERLVKEGRFVPSNPVGILTTSYYELLQNKVPLLGSSTACIVVLDRQSHRLHTANLGDSGFLVVRG 159

  Fly   186 GQVVHKSEEQQHYFNTPFQLSLPPPGHGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPE 250
            |:|||:|:|||||||||||||:.||....:||||||::||:.||.|:.||:||.||||:|||:|:
Zfish   160 GEVVHRSDEQQHYFNTPFQLSIAPPEAEGSVLSDSPDAADSSSFDVQLGDIILTATDGLFDNMPD 224

  Fly   251 DLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGGKPDDITVV 315
            .::||.|.::: ..:....|.||.|:|..|..|:.:..::||||..|..|.:..||||||||||:
Zfish   225 YMILQELKKLK-NTNYESTQQTAKSIAEQAHVLAYDPNYMSPFAQFACDNGLNVRGGKPDDITVL 288

  Fly   316 LATVA 320
            |:.||
Zfish   289 LSIVA 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12091	NP_001261261.1	PP2Cc	76..316	CDD:294085	135/240 (56%)
pptc7a	NP_001007379.1	PP2Cc	53..289	CDD:381813	133/236 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578462
Domainoid	1	1.000	263	1.000	Domainoid score	I1886
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I2774
OMA	1	1.010	-	-		QHG56397
OrthoDB	1	1.010	-	-		D546690at33208
OrthoFinder	1	1.000	-	-		FOG0002449
OrthoInspector	1	1.000	-	-		mtm6518
orthoMCL	1	0.900	-	-		OOG6_100742
Panther	1	1.100	-	-	LDO	PTHR12320
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2170
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770