DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12091 and Ppm1e

DIOPT Version :9

Sequence 1:	NP_001261261.1	Gene:	CG12091 / 38177	FlyBaseID:	FBgn0035228	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_796141.2	Gene:	Ppm1e / 320472	MGIID:	2444096	Length:	749	Species:	Mus musculus

Alignment Length:	383	Identity:	87/383 - (22%)
Similarity:	136/383 - (35%)	Gaps:	128/383 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SWTSRAISRA-----LRSSFST-LLETATGGGSGAAAKGATKSGATPGSSGAPRPRFVSVVCGFA 64
            |:.:.|::||     |:|..|. .:...|.|..|.......|...:..|      :...:.|.:.
Mouse   156 SFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFS------KLHEICCSWV 214

  Fly    65 KD-------------------NLRHK--------------YKPGKYGEDSWFKASTASADVMGVA 96
            ||                   |:|.|              :......|.::|          .|.
Mouse   215 KDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYF----------AVF 269

  Fly    97 DGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQRPVNLLAYSY---CELMEQK--KPILGSS 156
            ||.|     |:|...::|..:..  .||:...| |..|...|..::   .|...||  :..|...
Mouse   270 DGHG-----GVDAAIYASVHLHV--NLVRQEMF-PHDPAEALCRAFRVTDERFVQKAARESLRCG 326

  Fly   157 TACVLILNRETSTVHTANIGDSGFVVVREGQVV-----HK---SEEQQH---------YF----- 199
            |..|:...| .:.:|.|.:|||..::||:||.|     ||   .:|:|.         :|
Mouse   327 TTGVVTFIR-GNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRV 390

  Fly   200 NTPFQLS--LPPPGHGPNVLSDSPESADTMSFPVRDG--DVILIATDGVFDNVPEDLMLQVLSE- 259
            |....:|  :....|.|.:..|: :||.|    |.||  |.:::|.||.:|.|..|..::|:|:
Mouse   391 NGSLSVSRAIGDAEHKPYICGDA-DSAST----VLDGTEDYLILACDGFYDTVNPDEAVKVVSDH 450

  Fly   260 -VEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGGKPDDITVVL 316
             .|...|.   .|.|:.|...||.                       .|..|:|||::
Mouse   451 LKENNGDS---SMVAHKLVASARD-----------------------AGSSDNITVIV 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12091	NP_001261261.1	PP2Cc	76..316	CDD:294085	69/272 (25%)
Ppm1e	NP_796141.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..128
		7 X 2 AA tandem repeats of P-E	31..44
		PP2Cc	227..485	CDD:238083	72/306 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..537
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	608..627
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900