DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12091 and W09D10.4

DIOPT Version :9

Sequence 1:	NP_001261261.1	Gene:	CG12091 / 38177	FlyBaseID:	FBgn0035228	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_499362.1	Gene:	W09D10.4 / 176497	WormBaseID:	WBGene00012362	Length:	330	Species:	Caenorhabditis elegans

Alignment Length:	323	Identity:	139/323 - (43%)
Similarity:	197/323 - (60%)	Gaps:	23/323 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ALRSSF--------STLLETATGGGSGAAAKGATK-SGATPGSSGAPRP-----RFVSVVCGFAK 65
            |:|:.|        ||:...|...|....:.|::| ..::.||..:|.|     ..::...||.|
Worm    14 AVRAVFSASALDLGSTIGPEAISSGRRGLSSGSSKPKPSSEGSPSSPAPSAHVENVIASCAGFPK 78

  Fly    66 DNLRHK---YKPGKYGEDSWFKASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTCERLVQCS 127
            |.|...   ...|.:|:|:||.:...:..|:||||||||||.|||||..||..||:.||:.||..
Worm    79 DMLNGPSTVLDKGVFGDDAWFISRFKNTFVVGVADGVGGWRKYGIDPSAFSRRLMKECEKRVQKG 143

  Fly   128 HFNPQRPVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKS 192
            .|:||:|.:||.|::....|..:|: ||||||||::::|  .:::||:|||||:|||.|::|.||
Worm   144 DFDPQKPESLLDYAFRASAEAPRPV-GSSTACVLVVHQE--KLYSANLGDSGFMVVRNGKIVSKS 205

  Fly   193 EEQQHYFNTPFQLSLPPPGHGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVL 257
            .||.||||.||||:|||.|: ...:.|..:.||.....|:.||:||:|||||:||:.|..:|..|
Worm   206 REQVHYFNAPFQLTLPPEGY-QGFIGDKADMADKDEMAVKKGDIILLATDGVWDNLSEQQVLDQL 269

  Fly   258 SEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGGKPDDITVVLATVA 320
            ..::..:..|  |...|:|||.||.|:.:|:..||||:.||.:...|.||||||||:||..:|
Worm   270 KALDAGKSNV--QEVCNALALTARRLAFDSKHNSPFAMKAREHGFLAPGGKPDDITLVLLLIA 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12091	NP_001261261.1	PP2Cc	76..316	CDD:294085	117/239 (49%)
W09D10.4	NP_499362.1	PP2Cc	72..327	CDD:214625	124/260 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I1528
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6100
Inparanoid	1	1.050	242	1.000	Inparanoid score	I2091
Isobase	1	0.950	-	0	Normalized mean entropy	S1764
OMA	1	1.010	-	-		QHG56397
OrthoDB	1	1.010	-	-		D546690at33208
OrthoFinder	1	1.000	-	-		FOG0002449
OrthoInspector	1	1.000	-	-		otm14618
orthoMCL	1	0.900	-	-		OOG6_100742
Panther	1	1.100	-	-	LDO	PTHR12320
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R127
SonicParanoid	1	1.000	-	-		X2170
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820