DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12091 and PPM1L

DIOPT Version :9

Sequence 1:NP_001261261.1 Gene:CG12091 / 38177 FlyBaseID:FBgn0035228 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_640338.2 Gene:PPM1L / 151742 HGNCID:16381 Length:360 Species:Homo sapiens


Alignment Length:280 Identity:58/280 - (20%)
Similarity:108/280 - (38%) Gaps:95/280 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 ASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTCERLVQ-CSHFNPQRPVNLLAYSYCELMEQ 148
            |:.....:.|:.||.||..:     .|:..  .|..|.|.| ...:...:..::|  ||..::||
Human   116 ANKTHPSIFGIFDGHGGETA-----AEYVK--SRLPEALKQHLQDYEKDKENSVL--SYQTILEQ 171

  Fly   149 KKPILG---------------SSTACVL-ILNRETSTVHTANIGDS-GFVVVREGQVVHKSEEQQ 196
            :  ||.               :.|.|:: :|:.:..||  ||:||| |.:..::|..:..|.:.:
Human   172 Q--ILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTV--ANVGDSRGVLCDKDGNAIPLSHDHK 232

  Fly   197 HY----------------FNTPFQL--------SLPPPGHGP----NVLSDSPESADTMSFPV-- 231
            .|                ||..:::        ||   |..|    ||:...|   |.::|.:  
Human   233 PYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSL---GDYPLKNLNVVIPDP---DILTFDLDK 291

  Fly   232 RDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALS 296
            ...:.:::|:||::|....:..::.:.|...|..            ..|:::.|.|.:       
Human   292 LQPEFMILASDGLWDAFSNEEAVRFIKERLDEPH------------FGAKSIVLQSFY------- 337

  Fly   297 ARRNNIQARGGKPDDITVVL 316
                     .|.||:|||::
Human   338 ---------RGCPDNITVMV 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12091NP_001261261.1 PP2Cc 76..316 CDD:294085 58/278 (21%)
PPM1LNP_640338.2 PP2Cc 93..351 CDD:238083 58/280 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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