Protein Alignment Psa and pepN

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_415452.1
• Gene: pepN / 947253
• ECOCYCID: EG10696
• Length: 870
• Species: Escherichia coli
• Alignment Length: 922
• Identity: 208/922 - (22%)
• Similarity: 343/922 - (37%)
• Gaps: 234/922 - (25%)

  Fly   258 ITLNALDIVLDSVELHFE-CSKLKPEK--IVYSAENETATLEFAQEI-PAETQGVLHMSFTGELN 318
            :.||..|:.|.||.::.| .:..|.|:  :|.|...|..||:...|| ||             .|
E. coli    52 LRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPA-------------AN 103

  Fly   319 DKMKGFYRSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDR--VALSNM 381
            ..::|.|:|      |:   |..||.||...|......|.|.:.|.|...::..|.:  ..|||.
E. coli   104 TALEGLYQS------GD---ALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNG 159

  Fly   382 PVIKEDSLPDGLRRVRFDRTPIMSTYLVAVVVGEYDYVEG----KSDDGVLVRVFTPVGKREQGT 442
            ..:.:..|.:|...|::........||.|:|.|::|.:..    :|...|.:.::...|..::..
E. coli   160 NRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAP 224

  Fly   443 FALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQ 507
            :|:......:.:.::.|.:.|.|....::|:..|:.|||||.||..:...:||......:.....
E. coli   225 WAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYL 289

  Fly   508 SIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRAL- 571
            .|...:|||..|.|.||.||...|..|.|.||...|.:              .:|.:|:.:||:
E. coli   290 DIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRD--------------QEFSSDLGSRAVN 340

  Fly   572 ELDSLKNSHPIEV-----PVGHP------SEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMN 625
            .:::::....::.     |:.||      .|::..:....|.|||.||||:|..:||:.|:|||.
E. coli   341 RINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQ 405

  Fly   626 LYLTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKF 690
            ||..||.......:|...|:::||:.::|. ...|....|.|:|:|:.:...:.::.......:.
E. coli   406 LYFERHDGSAATCDDFVQAMEDASNVDLSH-FRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRT 469

  Fly   691 TADGSQADENCLW-------------VVPIS-----VSTSKNPTGIAKTFLLD------------ 725
            .|...||::..|.             |:|:.     |::..|.|...:||:.|
E. coli   470 PATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLC 534

  Fly   726 KSSMEVTLDNVDEDD-------------------------WIKINPG-------------TVGYY 752
            :.|..|.|:....|.                         :||:|..             ....:
E. coli   535 EFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAF 599

  Fly   753 RTRYSQEMLEQLMPAVEKMELPPLDRLG-LID--DMFAMVQAGHAST-------ADVLALVDSYR 807
            |.....|.::..: |.|.:.||.::.:. |.|  |..|:.:...|.|       ||.|..:.:..
E. coli   600 RAVLLDEKIDPAL-AAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATELADELLAIYNAN 663

  Fly   808 NETNYTVWTAITNSLTNLHILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLV 872
            .::.|.|               .|.|:.:      |.|.......|.:    ||.||..:|.|.
E. coli   664 YQSEYRV---------------EHEDIAK------RTLRNACLRFLAF----GETHLADVLVSK- 702

  Fly   873 LTRLVSFRSSDTIEEAKIRFRRHVNGTELLPA-----DLRTTCYKAVLQDGDEKIFNE--MLD-- 928
                              :|....|.|:.|.|     ..:..|..|::|:.|:|....  ::|
E. coli   703 ------------------QFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQNGLVMDKW 749

  Fly   929 -LYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDSVFVIVAVA-INPKGRDMAWE 991
             :.:||         |.|......::.|.:...|.||:..|.:.   :|.|.| .||..
E. coli   750 FILQAT---------SPAANVLETVRGLLQHRSFTMSNPNRIRS---LIGAFAGSNPAA------ 796

  Fly   992 FFKENNKQLLERYQGGFLL--------------SRLIKYLIENFASEERAKEVEEF-LQVNQIPG 1041
            |..|:....|      ||:              ||||:.||.  .....||..|:. ..:.|:.|
E. coli   797 FHAEDGSGYL------FLVEMLTDLNSRNPQVASRLIEPLIR--LKRYDAKRQEKMRAALEQLKG 853

  Fly  1042 CERTVSQAVETI 1053
            .|.......|.|
E. coli   854 LENLSGDLYEKI 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	113/425 (27%)
		ERAP1_C	741..1055	CDD:463368	75/362 (21%)
pepN	NP_415452.1	pepN	1..870	CDD:237585	208/922 (23%)