Protein Alignment Psa and Rnpep

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_112359.2
• Gene: Rnpep / 81761
• RGDID: 621137
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 130/598 - (21%)
• Similarity: 211/598 - (35%)
• Gaps: 155/598 - (25%)

  Fly   243 GKTVVQVNVKEPTTQITLNALDIVLDSVELHFECSKLKPEKIVYSAENETATLEFAQEIPAETQG 307
            ||..:::....|.     .|.::.|||    ..|.::....::.....:...|  .:.:|..||.
  Rat    61 GKATLELRCLLPE-----GASELRLDS----HSCLEVMAATLLRGQPGDQQQL--TEPVPFHTQP 114

  Fly   308 VLHMS----------------FTGELNDKMKGFYRSKYFGPN----GEERFAG------VTQFEA 346
            ..|..                |..||.      ||... ||.    ..|:.||      .||.:|
  Rat   115 FSHYGQALCVVFPKPCCAAERFRLELT------YRVGE-GPGVCWLAPEQTAGKKKPFVYTQGQA 172

  Fly   347 TDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDGLRRVRFDRTPIMSTYLVAV 411
            ...|..|||:|.||:|.|:...:.||....|:.:....:.    .|..:..|.....:.:||:|:
  Rat   173 VLNRAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTWER----RGPNKFFFQMNQPIPSYLIAL 233

  Fly   412 VVGEYDYVE----------------GKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYYKDYFN 460
            .:|:....|                .|.:...::..|...|::..|           ||....::
  Rat   234 AIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFG-----------PYVWGRYD 287

  Fly   461 IAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNL 525
            :.:..|        .|..|.|||..|     |||    ....|...:|:|..:.|||:|.|||||
  Rat   288 LLFMPP--------SFPFGGMENPCL-----TFV----TPCLLAGDRSLADVIIHEISHSWFGNL 335

  Fly   526 VTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYT-------RAL---ELDSLKNSH 580
            ||...|...|||||:.          ::.:..|.|......||       |||   .:|.....:
  Rat   336 VTNANWGEFWLNEGFT----------MYAQRRISTILFGAAYTCLEAATGRALLRQHMDVSGEEN 390

  Fly   581 P---IEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIG-EDTFRKGMNLYLTRHQYGNTCTEDL 641
            |   :.|.:....:.|:.::|..|.||...:..|...:| ::.|.|.:..|:...::.:...||.
  Rat   391 PLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDF 455

  Fly   642 ----WAALQEASSKNVSDV----MTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQAD 698
                .....|...|.|..:    ...|....|:|....:   .|....|::           .|:
  Rat   456 LEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPD---LSPGDSLMK-----------PAE 506

  Fly   699 ENC-LW---------VVPISVSTSKNPTGIAKTFLLDKSSMEVTL--DNVDE--DDWIKINPGTV 749
            |.. ||         :..:::||.|.   ....:.|||...:..|  .||.:  :.:.||:....
  Rat   507 ELAELWAASEPDMQAIEAVAISTWKT---YQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQN 568

  Fly   750 GYYRTRYSQEMLE 762
            ...|.|:.|.:|:
  Rat   569 AELRLRWGQIILK 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	107/482 (22%)
		ERAP1_C	741..1055	CDD:463368	6/22 (27%)
Rnpep	NP_112359.2	M1_LTA4H	24..484	CDD:341062	107/482 (22%)
		Leuk-A4-hydro_C	530..645	CDD:462686	13/55 (24%)