Protein Alignment Psa and npepps

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_001072690.1
• Gene: npepps / 780147
• XenbaseID: XB-GENE-1008338
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 880
• Identity: 484/880 - (55%)
• Similarity: 622/880 - (70%)
• Gaps: 33/880 - (3%)

  Fly   210 MAQKAKFERLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSV---- 270
            |..:..||||||:|.|.:|.|.|:|:|.:|||.||....|.|:..|.||.:|..||.:.:.
 Frog     1 MPDRRPFERLPTDVRPVNYGLCLKPDLIDFTFEGKLEATVEVQNATNQIVMNCADIDIITASYAP 65

  Fly   271 ----ELH---FECSKLKPEKIVYSAENETATLEFAQEIPAETQ---GVLHMSFTGELNDKMKGFY 325
                |:|   |.          |..|:|..||.|    |:..|   |:|.:.|.|||||||||||
 Frog    66 EGDEEIHATGFN----------YQNEDEKVTLSF----PSTLQKGAGMLKIDFVGELNDKMKGFY 116

  Fly   326 RSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLP 390
            ||||....||.|:|.|||||||||||.||||||||||||||:.|:|||||||||||.:|.....|
 Frog   117 RSKYATATGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDVILIVPKDRVALSNMNLIDRKPYP 181

  Fly   391 D--GLRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLP 453
            |  .|..|:|.|||||||||||.||||||:||.:|.|||||||:|||||.|||.||||||.|.||
 Frog   182 DDENLVEVKFARTPIMSTYLVAFVVGEYDFVETRSSDGVLVRVYTPVGKAEQGKFALEVAAKTLP 246

  Fly   454 YYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIA 518
            :||||||:.|||||:|||||:||:|||||||||||||||.:|:||||:....:|.:||.||||:|
 Frog   247 FYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELA 311

  Fly   519 HQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIE 583
            |||||||||||||||||||||:||::|:|||.|.|||||||||||:..||||.|||:|:||||||
 Frog   312 HQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALENSHPIE 376

  Fly   584 VPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEA 648
            |.||||||:|||||.|||:||||||||||||||::.||||||.|||:.|..|..|||||.:|::|
 Frog   377 VSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDEDFRKGMNQYLTKFQEKNAATEDLWESLEQA 441

  Fly   649 SSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGS-QADENCLWVVPISVSTS 712
            |.|.::.||.:||:..|||::.||||| .::..:|:|.|.||.|.|: .:|::..|:||||:.||
 Frog   442 SGKPIAAVMNTWTKQMGFPLICVESEQ-KEDSVVLKLSQKKFCASGAPNSDDSYQWMVPISICTS 505

  Fly   713 KNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAVEKMELPPLD 777
            ::|.......|:||..|.|.|:.|....|:|:||||||:|||:||..|||.|:|.:..:.|.|:|
 Frog   506 ESPASATVKILMDKPEMTVVLEGVKPHQWVKLNPGTVGFYRTQYSTTMLESLLPGIRDLSLQPVD 570

  Fly   778 RLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHILISHTDLMEDFHRFG 842
            ||||.:|:|::.:||..:||:||.:::::.||.|||||:.::.:|..|..|:||||..|:...|.
 Frog   571 RLGLQNDLFSLARAGMINTAEVLKVMEAFVNEPNYTVWSDLSCNLGILSTLLSHTDFHEEIQCFV 635

  Fly   843 RNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNGTELLPADLR 907
            |:::.|:..||||:|:.||.|||.|||.|||.:|.......|:|||:.||:.||:|..:|.||||
 Frog   636 RDVFSPIGQRLGWDPKPGEGHLDALLRGLVLGKLGKAGHQPTLEEARRRFKEHVDGRNVLSADLR 700

  Fly   908 TTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDS 972
            :..|..||:.||......|:.|::..|:.||::||.|.||...:..|:::|:.|::|.:||.||:
 Frog   701 SPVYVTVLKHGDNSTLETMMKLHKQADMQEEKNRIERVLGAIAEQDLIKKVLSFSLSEDVRPQDT 765

  Fly   973 VFVIVAVAINPK-GRDMAWEFFKENNKQLLERYQGGFLLSRLIKYLIENFASEERAKEVEEFLQV 1036
            |.||..||...| ||..||.|.|:|.::|..|||||||:|||||..::.|||::.|.|::.|...
 Frog   766 VCVIGGVAGGSKLGRKCAWNFVKDNWEELYNRYQGGFLISRLIKLSLDGFASDKMAAEIKAFFDA 830

  Fly  1037 NQIPGCERTVSQAVETIRLNAAWLQRDREQLAIFL 1071
            :..|..||||.|..|.|.|||.||:||.|.:..:|
 Frog   831 HPAPSAERTVQQCCENILLNAGWLKRDAEAIHHYL 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	289/450 (64%)
		ERAP1_C	741..1055	CDD:463368	145/314 (46%)
npepps	NP_001072690.1	M1_APN-Q_like	17..455	CDD:341064	289/451 (64%)
		ERAP1_C	534..847	CDD:463368	144/312 (46%)