Protein Alignment Psa and anpepa

DIOPT Version :9

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_001038326.1
• Gene: anpepa / 558452
• ZFINID: ZDB-GENE-030131-4781
• Length: 946
• Species: Danio rerio
• Alignment Length: 909
• Identity: 266/909 - (29%)
• Similarity: 450/909 - (49%)
• Gaps: 96/909 - (10%)

  Fly   218 RLPTNVVPRHYELLLQPNL----------KEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVEL 272
            |||.:::|..|.:.|||.|          :.:.|||.:.|:||..:.::::.|:..:|.:.:||:
Zfish    63 RLPDSLIPESYNVFLQPYLYAAITNNYTEQSYLFTGNSTVRVNCTKTSSRVFLHVHNINVTAVEV 127

  Fly   273 H-FECSKLKPEKIVYSAENETATLEFAQEIPAETQGV--LHMSFTGELNDKMKGFYRSKYFG--- 331
            . .:.::..|.|.....:|||..|:...|:..:..|.  :...|.|||.:.:.|||.|:|.|
Zfish   128 RKSDTNEKLPLKGYQIFKNETNFLDIHLEVAIKENGTYDIFTEFEGELLEDLTGFYASRYTGKGT 192

  Fly   332 -PNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDGLR- 394
             ...||||...:..:.||||..|||:||||:||.|.||::...:..|.||     ||..|..::
Zfish   193 DDEDEERFLATSLLQPTDARTVFPCFDEPAMKAVFTITIIHRPEIRARSN-----EDGDPRTIQI 252

  Fly   395 ------RVRFDRTPIMSTYLVAVVVGEYD---------------YVEGKS---DDGVLVRVFTPV 435
                  |..|..|..||:||:..::  ||               :|.|:|   |.|
Zfish   253 NGTDWIRTTFKPTKKMSSYLLGFII--YDTHTFSYVSKGTRTKIHVHGRSEAIDAG--------- 306

  Fly   436 GKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKN 500
                ...:|||....:|.:|::.|.:.||:.|:|.||:.||...||||||.::|:|:.:|.|.:.
Zfish   307 ----HADYALETTETILSHYENIFGLRYPMSKIDQIALPDFGVRAMENWGFISYQESGLLYDKET 367

  Fly   501 TSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTD 565
            .|...::.:...:.||:|||||||||||.||..|||.||:|:::.:..|..:  .:|:....|..
Zfish   368 ASTFDEEQVTTLIAHELAHQWFGNLVTMSWWNDLWLKEGFATYMSYKGVEAV--GWDLKDLIVLR 430

  Fly   566 MYTRALELDSLKNSHPIEV---PVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLY 627
            ....|.::|||..|||:.:   .|...|:|.|:||:|:|:|||:|:|||...:||:.|.||:.:|
Zfish   431 EIQTAFQMDSLNTSHPLSMNAYDVQTSSQISELFDDITYSKGAAVLRMLATRMGENEFMKGVKMY 495

  Fly   628 LTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSV--ESEQTSKNQRLLRLKQCKF 690
            |::.|:.||..:|||..|...:...|.:.|.:||:..|:||:::  ::..||:.|.||:
Zfish   496 LSKFQFENTVPKDLWECLNMDTHIKVDEFMKTWTEEVGYPVLTIITDTGDTSQEQFLLK------ 554

  Fly   691 TADGSQADENCLWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTR 755
                .:...:.||.:||...|.|........|..||....:....:.:|:|:..|....|:||..
Zfish   555 ----KEGGHDSLWHIPIKYMTLKAGVKEFPNFFTDKGPDPIPDFKIGKDNWLLANINCTGFYRVN 615

  Fly   756 YSQEMLEQLMPAVEKME--LPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAI 818
            |.:|...:|...::|..  :|.::|..||||.|.:.:|...:....|.|.....|:..|..|.:.
Zfish   616 YDEENWNRLTAQLQKNHRIIPLINRGQLIDDAFNLARAHRLNVTIALNLTKYLINDLEYIPWESA 680

  Fly   819 TNSLTNLHILISHTDLMEDFHRFGRNLYEPV-----AYRL-GWEPRDGENHLDTLLRSLVLTRLV 877
            ..:|....::...:::.....::.|||..|:     .|.: |..|.  |.:.|...:...:|...
Zfish   681 LKNLDFFTLMFDRSEVYGPIMKYLRNLVTPLYEEYEEYTINGTIPI--EKYTDQCNQVNAITVAC 743

  Fly   878 SFRSSDTIEEAKIRFRRHVNGTELLPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRI 942
            |....:.|..||..|..:.||:..:..:||...|.:.:..|||..:..:.:.|:...:..|:|::
Zfish   744 SNGLPECITMAKDLFSDYKNGSNPIHPNLRRAVYCSAVASGDEDDWEYVWEEYQKATVAAEKDKL 808

  Fly   943 SRALGCCGDLKLLRRVIDFAMS-SEVRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQG 1006
            ..||.|..::.||.|.:.:.:. |::|..|.|..|..:|.|..|:.:||:|.:.:...:.:.|..
Zfish   809 RYALSCTKEIWLLNRYLQYTLEPSKIRKMDMVSTISYIAQNVAGQPLAWDFIRGHWSYITQEYGA 873

  Fly  1007 GFL-LSRLIKYLIENFASEERAKEVEEFLQVNQIPG----CERTVSQAVETIRLNAAWLQRDRE 1065
            |.: |..|:..:.:.|::|...:|::: ||..||..    ..|.:.|.:|....|..|::.:::
Zfish   874 GIISLGSLLDVVTKRFSTEVELEELKQ-LQREQIQDDKWIAARALEQVIERTAANIIWVKENKQ 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	Peptidase_M1	218..604	CDD:279741	141/430 (33%)
		M1_APN_2	227..667	CDD:189008	163/484 (34%)
		ERAP1_C	742..1052	CDD:288671	78/323 (24%)
anpepa	NP_001038326.1	Peptidase_M1	63..472	CDD:279741	141/430 (33%)
		M1_APN_2	71..535	CDD:189008	163/485 (34%)
		ERAP1_C	602..923	CDD:288671	78/323 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820