Protein Alignment Psa and anpepa

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: XP_682987.2
• Gene: anpepa / 555478
• ZFINID: ZDB-GENE-130530-595
• Length: 960
• Species: Danio rerio
• Alignment Length: 896
• Identity: 280/896 - (31%)
• Similarity: 454/896 - (50%)
• Gaps: 61/896 - (6%)

  Fly   218 RLPTNVVPRHYELLLQPNL-----KEFTFTGKTVVQVNVKEPTTQITL--NALDIVLDSVELHFE 275
            |||..:.|::|.:.|.|.|     ..:.|||.:.|.....:.|..|.:  |.|::.|    .:..
Zfish    67 RLPDTLSPQYYNITLWPRLVMDANGMYIFTGISDVMFTCVKKTDLILIHSNKLNLTL----FNGR 127

  Fly   276 CSKLKPEKIVYSAENETATLEF-AQEIPAETQGV--------LHMSFTGELNDKMKGFYRSKYFG 331
            .:||.....|.:...::..|:. .|.:..:.:|.        ||..|||||.|.::|||||:|.
Zfish   128 HAKLTGMSGVTAPAIKSTWLQTQTQYLVIQLKGKLNPGKSYWLHTEFTGELADDLEGFYRSEYM- 191

  Fly   332 PNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIK-EDSLPDGL-- 393
            .:||::...:||.:||.||:.|||:||||:||.|:|.|:..:...||||...|: ||.:.|.:
Zfish   192 EDGEKKIIAITQMQATYARKAFPCFDEPAMKAVFNIILIHDRGMTALSNSQEIRTEDVIIDEMPV 256

  Fly   394 RRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKRE----QGTFALEVATKVLPY 454
            .|..|:.|..|||||||.||.::.|:..:...|||||::  ..|:.    ||.:||.:...:|.:
Zfish   257 TRTTFEPTARMSTYLVAFVVSDFSYINNEDKAGVLVRIW--ARKKAIDDGQGDYALSITQPILEF 319

  Fly   455 YKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAH 519
            ::.|:|.:|||.|.|.:|:.||::||||||||||||||.:|.||:.::...||.||..|.||:||
Zfish   320 FESYYNTSYPLSKSDQVALPDFNSGAMENWGLVTYRETALLYDPQTSANGNKQRIATVVSHELAH 384

  Fly   520 QWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPI-- 582
            .|||||||::||..||||||:||:||:|...|..|.::|..|.:.....||..:|||.:|||:
Zfish   385 MWFGNLVTLKWWNDLWLNEGFASYVEYLGADHAEPTWNIKDQIILYDMQRAFAVDSLTSSHPLSR 449

  Fly   583 -EVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQ 646
             |..|..|:||.|:|..|||:|||:|::||.:::.|..|.||::.||.:..:|::...|||..||
Zfish   450 KEEEVNTPAEISEMFSTISYSKGAAVLKMLSEFLTEPVFAKGLSNYLKQFAFGSSVHSDLWDHLQ 514

  Fly   647 EASS--------KNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENCLW 703
            ::..        ::|.::|:.|....||||:::::...:.:|:...:::.......|:.  |..|
Zfish   515 KSLDQAPGMKLPRSVHEIMSRWILQMGFPVITIDTRTGNVSQKHFLVEKDAVVERNSEF--NYEW 577

  Fly   704 VVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAV 768
            .|||  ...|......:.:||.||::...: .|.:.:|:..|....||:|..|.....|:|:..:
Zfish   578 FVPI--KWMKKGQVQDQMWLLQKSAIHKPM-KVSKGEWVLANHNVSGYFRVNYDHGNWERLLSQL 639

  Fly   769 E--KMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHILISH 831
            |  ...:|.::|..::||.|.:.:|...:....|........|..|..|.|...||.....|...
Zfish   640 ETNHQTIPVVNRAQILDDAFNLARASIINITLALRTTKYLVREREYIPWEAALRSLNYFFQLFDR 704

  Fly   832 TDLMEDFHRFGRNLYEPVAYRLG-----WEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIR 891
            .::......:.:...:|:....|     | .:....|.|...:.:.|:...........|..|..
Zfish   705 NEVYGALQAYLKKQVKPLFEHFGTISSNW-TKVPNGHTDQFTQIIALSLACGTGVEGCREITKSW 768

  Fly   892 FRRHVNGTELLP--ADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKL 954
            |::.:....:.|  .:||:|.|...:..|....:|....:::...:..|..::..||.|.....|
Zfish   769 FKKWMQNPRVNPIHPNLRSTVYCNAIAAGGADEWNFGWQMFQKATVAAEAVKLRAALACTKVPWL 833

  Fly   955 LRRVIDFAMSSE-VRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERY-QGGFLLSRLIKYL 1017
            |.|.::::::.| :|.||:...|..:|.|..|:.:||.|.:.|.....:.| .|.|..||||..:
Zfish   834 LNRYLEYSINPEKIRKQDATSTIGYIASNVIGQPLAWNFVRANWDYFFKVYGTGSFTFSRLISDI 898

  Fly  1018 IENFASEERAKEVEEFLQVNQIPGC---ERTVSQAVETIRLNAAWLQRDRE 1065
            ...|.:.....:::.|.:.|...|.   .:.:.||:|.......||..::|
Zfish   899 TSKFCTPFELSQLKRFQKDNAETGFGSGTQALQQAIERTTAKIKWLAENKE 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	184/468 (39%)
		ERAP1_C	741..1055	CDD:463368	72/327 (22%)
anpepa	XP_682987.2	None