Protein Alignment Psa and Lvrn

DIOPT Version :9

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: XP_038953134.1
• Gene: Lvrn / 502160
• RGDID: 1562779
• Length: 993
• Species: Rattus norvegicus
• Alignment Length: 931
• Identity: 260/931 - (27%)
• Similarity: 411/931 - (44%)
• Gaps: 161/931 - (17%)

  Fly   218 RLPTNVVPRHYELLLQPNLK-------EFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVEL--- 272
            |||..:||.||:|.|.|.|:       ..||||:..:.|.....|:.:.|::..:....||:
  Rat    94 RLPPWLVPLHYDLELWPRLQPDNLSTPSLTFTGRVNITVRCTVATSTLLLHSFFLNYKQVEVWGP 158

  Fly   273 ------HFECSKLKPEKIVYSAENETATLEFAQEIPAETQGVLHMSFTGE-LNDKMKGFYRSKYF 330
                  :....::..|.:.::.:.:...|:..|.:...:...|:..|:|: |.:..:|.:.:.|
  Rat   159 LAPDTRNATVGRVPLENVWFALDMQYVVLDLGQSLDPGSSYELNFDFSGQVLQEGSEGLFLNLY- 222

  Fly   331 GPNGEERFAGV--TQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPD-- 391
              ..|::...:  ||.|.|.||..|||:||||:||||:||::.....|||||||.:.:....|
  Rat   223 --TDEDQLRALIATQMEPTFARHVFPCFDEPALKATFNITIIHHPGYVALSNMPQLGQSHRIDVN 285

  Fly   392 GLR--RVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQG--TFALEVATKVL 452
            |.|  ...|..||.|.|||||:|:.::||| .:::.|..:||:........|  .||......|.
  Rat   286 GSRWTVTSFHTTPRMPTYLVALVICDFDYV-SRTERGKEIRVWARKDDIADGYLDFAANHTGPVF 349

  Fly   453 PYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTV-GHE 516
            .:.:|.|||:|||||.|:||:..|..||||||||:.:..:.:|  ..:..|..|:::.|:: .||
  Rat   350 SFLEDLFNISYPLPKTDIIALPTFVNGAMENWGLMIFDASLLL--ELDDDLPEKRAMILSILSHE 412

  Fly   517 IAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHP 581
            :.||||||||||.||.::|||||:||:.|....::.:|:......|...:....||.|....|..
  Rat   413 VGHQWFGNLVTMSWWNNIWLNEGFASYFEVGLTNYFYPKVPRNMIFFLTVLHDILEDDHSLESRA 477

  Fly   582 IEVPVGH---PSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWA 643
            :..||.:   ..||:.:||..:|.|||.:..||..::.:..|...:..||....|.|...:|||.
  Rat   478 VSTPVENFTETREINRLFDIYTYKKGACMAWMLAGFLSQHLFINALKSYLETFSYSNAEQDDLWR 542

  Fly   644 ALQEASSK--------NVSDVMTSWTQHKGFPVVSVESE-----------QTSKNQRLLRLKQCK 689
            .:|.|..:        .|..:|.|||...||||:::.:.           :..:||.||
  Rat   543 HIQMAIDEQSIIHLPATVKRIMDSWTHQSGFPVITLNASTGVVKQEPFYLERVENQTLL------ 601

  Fly   690 FTADGSQADENCLWVVPISVSTSKNPTGIAKTFL-LDKSSM---EVTLDNVDEDDWIKINPGTVG 750
                     .:..|:|||  ...||  ||.:..: ||||||   .:.|.:.| .||:.:|....|
  Rat   602 ---------SHNTWIVPI--FWMKN--GITQPLVWLDKSSMIFPGMKLSDSD-SDWVILNFNVTG 652

  Fly   751 YYRTRYSQEMLEQLMPAVEK--MELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYT 813
            |||..|.:...::|...:||  ..:|.::||.|:.|.||:.:..:......|.|......|....
  Rat   653 YYRVNYDKLGWKKLNQQLEKDPKAIPVINRLQLVSDAFALSKNNYIEIETALDLTKYIAKEDEIL 717

  Fly   814 VWTAITNSLTNLHILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVS 878
            ||..:..:|.|..:                 :|:...|           :|..||:...|.||
  Rat   718 VWFEVLVNLINREV-----------------VYDVKNY-----------YLYPLLKKYFLKRL-- 752

  Fly   879 FRSSDTIEEAKIRFRR---HVNGTELLPAD--LRTTCY--------------------------- 911
             .|..||..|.||...   ..|...|||..  ..|.|:
  Rat   753 -NSIWTIYSAIIRENMASLQDNFLSLLPLKKFFETACWLGLEDCLQLSRELFRKWMAHPETAIPP 816

  Fly   912 ---KAVLQD----GDEKIFNEMLDLY-RATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVR 968
               |.||.:    |..|.::.:.:|| ..|:..|:...:..|:||..|.:.|.|.:::.::....
  Rat   817 QIEKVVLCNAIALGSNKDWDFLFNLYINKTEEQEDLFHLVHAMGCSKDPRTLNRFMEYDITVFPS 881

  Fly   969 AQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQGGFLLSRLIKYLIENFASEERAKEVEEF 1033
            ..:...:|..||.:..||.:|.:|...|   .:..|:...|...|.:|.:..:.:      :.|.
  Rat   882 RFNETNLIEVVAESEVGRYVAKDFLINN---WVAVYESPSLSPLLQQYFVSVWTT------IAEH 937

  Fly  1034 LQVNQIPGCE-RTVSQAVETI 1053
            ..|:....|: |:....|..:
  Rat   938 SSVHLREDCQHRSAGYGVAAV 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	Peptidase_M1	218..604	CDD:279741	139/414 (34%)
		M1_APN_2	227..667	CDD:189008	155/476 (33%)
		ERAP1_C	742..1052	CDD:288671	75/352 (21%)
Lvrn	XP_038953134.1	M1_APN-Q_like	102..569	CDD:341064	153/472 (32%)
		ERAP1_C	643..915	CDD:403137	67/305 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920