Protein Alignment Psa and CG46339

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Alignment Length: 1166
• Identity: 303/1166 - (25%)
• Similarity: 495/1166 - (42%)
• Gaps: 197/1166 - (16%)

  Fly    68 TTGDNNSSPRIVANYYRTAPVNPPKQQNPKPSGAADKTTSVKHLFRAESGHLNALISSKQFVK-- 130
            |.|...|:....|:...:|..:......|..:|:|..:::     .|..|....|::..:..|
  Fly    52 TAGTPTSAKNASASASASASASLSSPAGPSAAGSASTSSA-----PAGGGPWQGLVAKLRNFKLD 111

  Fly   131 ----VQKQFYRDFSSVS--LGAPLKSS-------DAPLLGDLCSQYRAILA---------HTSA- 172
                ::|:|:.|:.|..  ||..||:.       :.|..|...|:...|:|         .|.|
  Fly   112 DTKNIRKRFHFDYISKDRFLGGQLKTKNGQKYVFNGPPSGVYVSKACLIIAAFITVLALLFTIAI 176

  Fly   173 ------------DVIPGQ--DRHHPGCNYQQIRRAHTQLLSKEQQLEQ----------------- 206
                        :|.|..  ...||..|...|:.|....::....|:.
  Fly   177 TYFVTRQGLNPKEVTPPSCITADHPDVNATPIQTAGWVSMNSPPPLQAATPTPMASPTPTNTPTV 241

  Fly   207 ERKMAQKAKFERLPTNVV------------------------------------PRHYELLLQPN 235
            ...:|..|..|:....:|                                    |.||.||::|:
  Fly   242 TTTLAMPASSEKPEIRMVDPKVGDIPVVEPAAGEVEDNTTKPINRPLKLYEGWRPLHYSLLIEPS 306

  Fly   236 LKEFTFTGKTVVQV--NVKEPTT--QITLNALDIVLDSV-----------------ELHFECSKL 279
            :......|...:::  :|.:.|:  .|.|:..::.:.:|                 :|.|:..
  Fly   307 VATSISNGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSD-- 369

  Fly   280 KPEKIVYSAENETATLEFAQEIPAETQ--GVLHMSFTGELNDKMKGFYRSKYFGPNGE-ERFAGV 341
                  |..:|.|..:..::.:..|||  .:|.:.|..::.|.::|.|::.|..|:.: |.:...
  Fly   370 ------YGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMIS 428

  Fly   342 TQFEATDARRCFPCWDEPAIKATFDITLVVPKD-RVALSNMPVIKEDSLPDGLRRVR-------F 398
            |||...||||.|||:|.|.:||.|.|::|.|.. ::||||||       ..|.||.|       |
  Fly   429 TQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMP-------KSGSRRFRRGFIRDDF 486

  Fly   399 DRTPIMSTYLVAVVVGE-YDYVEGKSDDGVLVRVFTPVGKREQGT----FALEVATKVLPYYKDY 458
            :.||.|.|||||.:|.. .|......|.|:..||  .:..|.|..    :|.::..|.||||:|:
  Fly   487 ETTPKMPTYLVAFIVSNMVDSRLASQDSGLTPRV--EIWTRPQFVGMTHYAYKMVRKFLPYYEDF 549

  Fly   459 FNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLM----RKQSIALTVGHEIAH 519
            |.|...|||:||:::.||...|||||||:|:|::.:|| |::..|.    ..|.:|..:.||:||
  Fly   550 FGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLV-PEDLQLASSSEHMQVVAGIIAHELAH 613

  Fly   520 QWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEV 584
            ||||||||.:||..|||.||:|.::.:..:.|..||:..........:..::|.|:...||.|..
  Fly   614 QWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISF 678

  Fly   585 PVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEAS 649
            .|...:::..|||.|||:||..::|||:..:|:..||......|.:..|||...:||||.|....
  Fly   679 DVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHG 743

  Fly   650 SK--------NVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENCLWVVP 706
            .:        :|..:|.||....|:|||:||.....     |.|:|.::........:...|.:|
  Fly   744 HEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGAD-----LVLRQERYLLPSKNTADQSTWFIP 803

  Fly   707 ISVSTSKNPTG--IAKTFLLDKSSMEVTLDNV-----DEDDWIKINPGTVGYYRTRYSQEMLEQL 764
            |:..|.:...|  |...::..:...|:.:.||     :.|:.|.:|....||||..|  :|...|
  Fly   804 ITFETDELRKGDNIPTHWMRSEDEEELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNY--DMTSWL 866

  Fly   765 MPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADV-----LALVDSYRNETNYTVWTAITNSLTN 824
            ........||.:.|..|:||...:.||.:. |.|:     :.|.|:..:|   .:|.|....|..
  Fly   867 ALKKNFSTLPRITRAQLLDDALHLSQAEYL-TYDIPLTFLMELFDAVDDE---LLWIAAKPGLNY 927

  Fly   825 LHILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAK 889
            |...:......|.|..|.:.:..|.....|....|.|:||....|:||......|......::|:
  Fly   928 LIYNLKREPAYETFRAFMKFIVRPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNYDRCTQKAQ 992

  Fly   890 IRFRRHVNGTELLP--ADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDL 952
            ::||..:...:..|  .:|::..|...|.:|....:......|:.|....|::.|..:|||....
  Fly   993 MKFREWMRDPKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKP 1057

  Fly   953 KLLRRVIDFAM--SSEVRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQGGF-LLSRLI 1014
            .||.:.::..:  :|.:..||......|||.|..|.::|::|.:.|.|:::|.|..|| .||.:|
  Fly  1058 WLLSKYLNMTINPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMI 1122

  Fly  1015 K----YLIENFASEERAKEVEEFLQVNQIPGCERTVSQAVETIRLNAAWLQRDREQLAIFL 1071
            |    |:.::: .:.:..::....:...:...|..:..|:|.:..|..|.......|..||
  Fly  1123 KSLTIYMNKDY-HKHQLLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFL 1182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	159/483 (33%)
		ERAP1_C	741..1055	CDD:463368	80/327 (24%)
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	159/484 (33%)
		ERAP1_C	846..1126	CDD:463368	76/285 (27%)