Protein Alignment Psa and npepps

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_001157499.1
• Gene: npepps / 407726
• ZFINID: ZDB-GENE-060524-3
• Length: 872
• Species: Danio rerio
• Alignment Length: 874
• Identity: 487/874 - (55%)
• Similarity: 621/874 - (71%)
• Gaps: 22/874 - (2%)

  Fly   210 MAQKAKFERLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHF 274
            |.::..|.||||:|.|.:|.|.|:|:|.:|||.||....|.|.:.|.||.:|..||  |.:...|
Zfish     1 MPERRPFVRLPTDVYPVNYGLRLKPDLVDFTFEGKLEAAVEVTQGTNQIVMNCADI--DIITASF 63

  Fly   275 ---ECSKLKPEKIVYSAENETATLEFAQEIPAETQ---GVLHMSFTGELNDKMKGFYRSKYFGPN 333
               ...::......|..|:|..||.|    |:..|   |.|.:.|.||||||||||||||| ..:
Zfish    64 VPDGGEEINATGFNYQNEDEKVTLCF----PSTLQKGSGSLKIDFVGELNDKMKGFYRSKY-SSS 123

  Fly   334 GEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLP----DGLR 394
            ||.|:|.|||||||||||.|||||||||||||||||:|||||||||||.|:  |..|    ..|.
Zfish   124 GEVRYAAVTQFEATDARRAFPCWDEPAIKATFDITLIVPKDRVALSNMNVV--DRKPYAEDQSLV 186

  Fly   395 RVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYYKDYF 459
            .|:|..||||||||||.|:||||:||.:|.|||.|||:|||||.|||.||||||||.||:|||||
Zfish   187 EVKFATTPIMSTYLVAFVIGEYDFVESQSSDGVTVRVYTPVGKAEQGKFALEVATKTLPFYKDYF 251

  Fly   460 NIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGN 524
            ::.|||||:|||||:||:|||||||||||||||.:|:||||:....:|.:||.||||:|||||||
Zfish   252 SVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCASSRQWVALVVGHELAHQWFGN 316

  Fly   525 LVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHP 589
            |||||||||||||||:||::|:|||.|.|||||||||||:..|||||:||:|.|||||||.||||
Zfish   317 LVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRALDLDALDNSHPIEVDVGHP 381

  Fly   590 SEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSKNVS 654
            ||:|||||.|||:||||||||||:|||::.||||||.||.:.|:.|..|||||..|::||.|.::
Zfish   382 SEVDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQASGKPIA 446

  Fly   655 DVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENC-LWVVPISVSTSKNPTGI 718
            .||.|||:..|||::.|:.||.. :.|:|::.|.||.|.|.:.||:| .|:||||:.||::|:..
Zfish   447 AVMNSWTKQMGFPIIVVDQEQHG-SDRVLKISQKKFCASGPRNDEDCPNWMVPISICTSEDPSCT 510

  Fly   719 AKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAVEKMELPPLDRLGLID 783
            ....|||:....|.:.||..|.||||||||||:||.:||..|||.|:|.:..:.|.|:|||||.:
Zfish   511 KTKILLDQPETTVNITNVAPDHWIKINPGTVGFYRIQYSSAMLESLLPGIRDLTLLPVDRLGLQN 575

  Fly   784 DMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHILISHTDLMEDFHRFGRNLYEP 848
            |:|::.:||..||.:||.:::::.||.|||||:.::.:|..|..|:||||..||...|.|:|:.|
Zfish   576 DLFSLARAGMISTVEVLKVMEAFVNEPNYTVWSDLSCNLGVLSSLLSHTDFHEDIQEFIRDLFTP 640

  Fly   849 VAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNGTELLPADLRTTCYKA 913
            :..:|||:.|.||.|||.|||.|||.:|.......|:|||:.|||.||.|.::|.||||:..|..
Zfish   641 IGMKLGWDSRTGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFREHVEGKQILSADLRSPVYLT 705

  Fly   914 VLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDSVFVIVA 978
            ||:.||....:.||.|::..|:.||::||.|.||......|::||::||:|.|||.||:|.||..
Zfish   706 VLKHGDSTTLDTMLKLHKQADMQEEKNRIERVLGAIPAPDLIQRVLNFALSEEVRPQDTVSVIGG 770

  Fly   979 VAINPK-GRDMAWEFFKENNKQLLERYQGGFLLSRLIKYLIENFASEERAKEVEEFLQVNQIPGC 1042
            ||.:.| ||..||:|.|:|.::|..|||||||:|||||..::.||.::.|.||:.|.:.:..|..
Zfish   771 VAGSSKQGRKAAWKFVKDNWEELHNRYQGGFLISRLIKLTVDGFAIDKMAAEVKSFFESHHAPAA 835

  Fly  1043 ERTVSQAVETIRLNAAWLQRDREQLAIFL 1071
            ||||.|..|.|.||||||:||.:.:..:|
Zfish   836 ERTVQQCCENILLNAAWLKRDADDIHQYL 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	286/444 (64%)
		ERAP1_C	741..1055	CDD:463368	152/314 (48%)
npepps	NP_001157499.1	M1_APN-Q_like	17..454	CDD:341064	286/445 (64%)
		ERAP1_C	533..846	CDD:463368	151/312 (48%)