Protein Alignment Psa and Trhde

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_666353.2
• Gene: Trhde / 237553
• MGIID: 2384311
• Length: 1066
• Species: Mus musculus
• Alignment Length: 1065
• Identity: 311/1065 - (29%)
• Similarity: 527/1065 - (49%)
• Gaps: 118/1065 - (11%)

  Fly    92 KQQNPKPSGAADKTTSVKHLFRAESGHLNALI--------------------SSKQFVKVQKQFY 136
            |::..|....|:|::|.   |.|..|..:|.:                    ::::.:.|.|:..
Mouse    21 KKRKKKEEEGAEKSSSP---FAATMGEDDAALRASGRGLSDPWADSVGVRPRTTERHIAVHKRLV 82

  Fly   137 RDFS-------SVSLGAPLKSSDAPLLGDLCSQYRAILA----------HTSADVIPGQDR--HH 182
            ..|:       :|::.|.|.|    |..|.|....|:..          ..|....||..|  ||
Mouse    83 LAFAVSIVALLAVTMLAVLLS----LRFDECGASAAMPGTDGGLGGFPERDSNSSFPGSARRNHH 143

  Fly   183 PGCNYQQIRRAHT---QLLSKEQQLEQERKMAQKAKFERLPTNVVPRHYELLLQPNLKEFTFTGK 244
            .|....|......   ...|.:...|:||:..|.....||..::.|.||.|:|...::.|||:|:
Mouse   144 AGGESSQRESGEVGTPGTPSAQPPSEEEREQWQPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGE 208

  Fly   245 TVVQVNVKEPTTQITLNALDIVLDSVELHFECSKLKPEKIVYSA----------ENETATLEFAQ 299
            ..|::..:..|..:.|:|..:.::.|::        .|...:.|          :.:...:...:
Mouse   209 VNVEIACRNATRYVVLHASRVAVEKVQV--------AEDRAFGAVPVAGFFLYPQTQVLVVVLNR 265

  Fly   300 EIPAETQGVLHMSFTGELNDKMKGFYRSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPAIKAT 364
            .:.|:....|.:.:...:.:::.||:||.|. .:||.||.|||||..|.||:.|||:|||..|||
Mouse   266 TLDAQRHYNLKIIYNALIENELLGFFRSSYV-IHGERRFLGVTQFSPTHARKAFPCFDEPIYKAT 329

  Fly   365 FDITLVVPKDRVALSNMPVIKEDSLPDGLRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLV 429
            |.|::......::||||||.......||.....|.:||:||||.:|..:..:.|.|..:..||:|
Mouse   330 FKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVV 394

  Fly   430 RVFT--PVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRET 492
            |::.  ...:|..|.:||.:..:::.:|:|||.:.|.|||:||:|:......|||||||..:.|.
Mouse   395 RLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQ 459

  Fly   493 FVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYD 557
            .:|:||..:|:.....:.:.:.|||.|||||:|||..||..:||.||:|.:.||:...:|:|.::
Mouse   460 RILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPAWN 524

  Fly   558 IWTQ-FVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFR 621
            :..| |:||:....:.||.|.:|||:...|...::||.:||.|:|.|||::||||.:::|...|:
Mouse   525 MEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQ 589

  Fly   622 KGMNLYLTRHQYGNTCTEDLWAALQEASSK-----NVSDVMTSWTQHKGFPVVSVESEQTSKNQR 681
            :|:..|||.|:|||....|||..|.||..:     |:.:||..||...|:||:::....|::|:.
Mouse   590 RGLQDYLTIHKYGNAARNDLWNTLSEALRRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRI 654

  Fly   682 LLRLKQCKFTAD-GSQA------DENCLWVVPISVSTSKNPTGIAKTFLL--DKSSMEVTLDNVD 737
            |  :.|..|..| |::.      :.:.||.:|:::... |.:.::...::  ...|....:..:|
Mouse   655 L--ITQQHFIYDIGAKTKALQLQNSSYLWQIPLTIVVG-NRSHVSSEAIIWVSNKSEHHRIAYLD 716

  Fly   738 EDDWIKINPGTVGYYRTRYS----QEMLEQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTAD 798
            ...||..|....||:|..|.    :.:::||:...|.:.:.  :|..||||.|::.:||:.....
Mouse   717 RGSWILGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVS--NRAALIDDAFSLARAGYLPQNI 779

  Fly   799 VLALVDSYRNETNYTVWTAITNSLTNLHILISHTDLMEDFHRFGRNLYEPVA---YRLGWEPRDG 860
            .|.::.....|.::..|.|.:.:|..|..|:   |.||:::.|...:.:.||   .:||| ||:.
Mouse   780 PLEIIRYLSEEKDFLPWHAASRALYPLDKLL---DRMENYNIFNEYILKQVATTYIKLGW-PRNN 840

  Fly   861 EN---------HLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNGT-ELLPADLRTTCYKAVL 915
            .|         |.:  ||..|:....||.:....::|.......::.. ..:|.::|...|...:
Mouse   841 FNGSLVQASYQHEE--LRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGV 903

  Fly   916 QDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSE-VRAQDSVFVIVAV 979
            ...||.::..:...:.:|....|:..:..||.|..|..||.|:::.:::|| |..||::.||:.|
Mouse   904 SLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLSRLLNLSLNSEVVLDQDAIDVIIHV 968

  Fly   980 AINPKGRDMAWEFFKENNKQLLERY-QGGFLLSRLIKYLIENFASEERAKEVEEFLQVNQIPG-C 1042
            |.||.|||:||:||::..|.|..|| :..|:.|:||..:.|...:|...||::.|::  ...| .
Mouse   969 ARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMK--SYDGVA 1031

  Fly  1043 ERTVSQAVETIRLNAAWLQRDREQL 1067
            ..:.|:||||:..|..|.:..:::|
Mouse  1032 SASFSRAVETVEANVRWKRFYQDEL 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	160/452 (35%)
		ERAP1_C	741..1055	CDD:463368	95/333 (29%)
Trhde	NP_666353.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..176		12/57 (21%)
		M1_APN-Q_like	190..635	CDD:341064	160/453 (35%)
		ERAP1_C	720..1044	CDD:463368	95/333 (29%)