Protein Alignment Psa and R03G8.6

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_510175.1
• Gene: R03G8.6 / 181438
• WormBaseID: WBGene00011000
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 813
• Identity: 199/813 - (24%)
• Similarity: 355/813 - (43%)
• Gaps: 156/813 - (19%)

  Fly   205 EQERKMAQKAKFERLPTNVVPRHYELLLQPNL---------KEFTFTGKTVVQVNVKEPTTQITL 260
            |.:.::|..|.: |||.:|.|.||::.::..|         .:.||.|...:.:::||.|.::.|
 Worm    19 ELDARIADVASY-RLPRHVSPSHYDIHIKTYLPGYGWKADENKITFEGNVNILLDIKETTDKLVL 82

  Fly   261 NALDIVLDSVELHFECSKLKPEKIVYSAENETATLEFAQEIPAETQGVLHMSFTGELNDKMKGFY 325
            ::..:.:.|.....:...:.........|::..|......:..::...:.::|.|::.....|.:
 Worm    83 HSSSLNIISATFQSDEQNVSISHWNVQTESQFLTFYLNNTVKVQSSAGIQINFQGKVRTDGLGLF 147

  Fly   326 RSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLP 390
            .:.....:|.......||||...||...||:|||..|||::::|..|....|||| .:..|..:.
 Worm   148 ATNSTREDGTVMTNFATQFETIFARNMIPCFDEPEFKATWNVSLEHPTGSTALSN-GIEVESKVN 211

  Fly   391 DGLRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYY 455
            |..:...:.:|..||:|::|:.:|:..:.|...::||.:||:|.....::...||.::..||..:
 Worm   212 DDWKTTTYKKTLKMSSYILALFIGDIQFKETILNNGVRIRVYTDPVNIDRVDHALNISRIVLEGF 276

  Fly   456 KDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQ 520
            :..|.|.||:.|:|.:::.:|..|||||||||.:....::.||        ..:...|.||||||
 Worm   277 ERQFGIRYPMEKLDFVSVQNFKFGAMENWGLVIHNAYSLIGDP--------MDVTEIVIHEIAHQ 333

  Fly   521 WFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVP 585
            ||||||||::|.|:|||||:||::....:..|.|:|...|.::...:...:      |...:.:.
 Worm   334 WFGNLVTMKYWDHIWLNEGFASYMTSYGLTFLDPDYQRDTFYLNCQFNPQI------NDGGVSLN 392

  Fly   586 VGHPSEIDEIFDEIS--YNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEA 648
            .|  ..:..:.:..:  |.||.|.:|||.:..|.:.|.:.:..||.::||.|....||:.|.:.:
 Worm   393 FG--KNLSSVMNNAATVYMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQYDNVDDNDLYEAFRTS 455

  Fly   649 SSK--------NVSDVMTSWTQHKGFPVVSVESE-------QTSKNQRLLRLKQCKFTADGSQAD 698
            |..        ::......||...|||.:.|.::       |:...:..|.|.:|.:.
 Worm   456 SETLDTNGKPFDIEKFARCWTHQNGFPTIQVSNDNGIATLTQSHLYEPQLMLNECDYK------- 513

  Fly   699 ENCLWVVPISVSTSKNPTGIAKTFL--LDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEML 761
                |.:||   ..:.| |.|:..:  |:::|..:.|   ..||.:.||..::|||...||.:|.
 Worm   514 ----WDIPI---WYQEP-GEARVQMAWLNRNSTSLEL---VADDSVIINANSIGYYEVLYSDKMY 567

  Fly   762 EQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSL-TNL 825
            |::                                |:.:|:     |.:.|:|     ||| ..|
 Worm   568 EKI--------------------------------AEQVAI-----NVSRYSV-----NSLRRTL 590

  Fly   826 HILISHT-DLMEDFHR---------FGRN---LYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLV 877
            |.:..:: |.:..||.         ||.|   .:|.|.|               |:.::..|...
 Worm   591 HDVFRYSRDGLTPFHNAFIIAYVLVFGENEILRHESVLY---------------LVDAVYNTNNK 640

  Fly   878 SFRSSDTIEEAKIRFRRHVNGTELLPADLR----TTCY----------KAVLQDGDEKIFNEMLD 928
            |..:|..||..| .....:...||.|..::    ::||          :|::|   .|:....:|
 Worm   641 SIVNSKDIETVK-GLVNQIENFELFPKCVQSQTFSSCYQKRIPQNINLRAIMQ---LKLSQNTMD 701

  Fly   929 L---YRATDLHEEQDRISRALGCCGDLKLLRRV 958
            |   :....::||.....:.:..|...:.|:::
 Worm   702 LIVAWAENGVNEEAKLGPKLMLGCSTKENLKKI 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	122/453 (27%)
		ERAP1_C	741..1055	CDD:463368	49/249 (20%)
R03G8.6	NP_510175.1	M1_APN-Q_like	39..477	CDD:341064	122/454 (27%)
		ERAP1_C	548..>608	CDD:463368	22/101 (22%)