Protein Alignment Psa and F49B2.6

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_493503.2
• Gene: F49B2.6 / 173297
• WormBaseID: WBGene00009865
• Length: 1082
• Species: Caenorhabditis elegans
• Alignment Length: 906
• Identity: 258/906 - (28%)
• Similarity: 466/906 - (51%)
• Gaps: 61/906 - (6%)

  Fly   199 SKEQQLEQERKMAQKAKFE---------RLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEP 254
            ::||:.||..:...||..|         |||....|..|:|.|.|||..........:::.:|..
 Worm   171 TEEQEEEQSGEKFVKANKECTNITWYSSRLPRTAEPIDYDLTLHPNLTNGEVEASVSIRILIKND 235

  Fly   255 TTQITLNALDIVLDSVELHFECSKLKPEKIVYSAENETATLEFAQEIPAETQGVLHMSFTGELND 319
            |..:.|||.::.:.|.::..:.:|:|.:.:..:...:.| .:.|:.:......||.:.::.::..
 Worm   236 TKLLILNAENLEMKSFDITKKGAKVKADFVKCAVMTQWA-WKLAKRLHKGDHIVLTIYYSAQMKS 299

  Fly   320 KMKGFYRSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVI 384
            .::|.|.|.:.|.:|::..:..||||.|.||:..||:|||..||||.:.::.....:|.|||.::
 Worm   300 DLQGLYFSTHLGTDGKKTKSAATQFEPTFARKMLPCFDEPNFKATFQVAIIRNPHHIARSNMNIL 364

  Fly   385 KEDSLPDGLRRVRFDRTPIMSTYLVAV-VVGEYDYVE---GKSDDGVLVRVFTP----VGKREQG 441
            ......:||.:..|:::..|||||:|| |:..|.|::   ..:...:.||::.|    .|:.|
 Worm   365 ISKEYKNGLIKDVFEKSVKMSTYLLAVAVLDGYGYIKRLTRNTQKAIEVRLYAPQDMLTGQSE-- 427

  Fly   442 TFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRK 506
             |.|:...:.|.:::|||||:|||.|:||:|:.|||.||||||||||:|::.:|.:.:..|::.|
 Worm   428 -FGLDTTIRALEFFEDYFNISYPLDKIDLLALDDFSEGAMENWGLVTFRDSALLFNERKASVVAK 491

  Fly   507 QSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRAL 571
            :.|||.:.||||||||||||||:||..::||||:|:::|:.||.||||::.|.::|..:....:.
 Worm   492 EHIALIICHEIAHQWFGNLVTMDWWNEVFLNEGFANYMEYKCVEHLFPDWSIMSRFYAENLAFSQ 556

  Fly   572 ELDSLKNSHPIEVPVGHPSEIDE----IFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQ 632
            |.|...:|..||      |:.|:    :||.|:|:|.|::|.|:.:..|:..|:..:..||.::.
 Worm   557 EPDGFLSSRAIE------SDDDDSLLNLFDAINYHKAAAIIHMIAEMAGQKNFQNALVEYLNKYA 615

  Fly   633 YGNTCTEDLWAALQE----ASSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFT-A 692
            |.|....|||..:::    ..:.::.|:..::|...|:|:::||    ..::.:|...|.:|. |
 Worm   616 YSNAIGVDLWKIVEKHANLQGTVSIPDLAKAYTTQVGYPLLTVE----RTDEGVLVHNQTRFLFA 676

  Fly   693 DGSQADE---NCLWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRT 754
            :|.:|:|   :..|.:|||...|::..  .|...:......||.:.. .:||:.:|.|.|||::.
 Worm   677 EGDKAEEKRGDWKWPIPISYRDSEHRR--KKQHWIQADDKNVTWETT-SNDWLILNTGGVGYFKV 738

  Fly   755 RYSQEMLEQLMPAVEK--MELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTA 817
            .|..|...:|:..:::  ..:.|:||..::.|.|.:.:....:.:....|::....||:...|:.
 Worm   739 LYDPETYRKLVKQLQRNHTTISPIDRSMILVDSFDLSKTSLLNISVYFDLLEYVEKETDKMTWSI 803

  Fly   818 ITNSLTNLHILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSS 882
            :...|..:..||..:|.::.:..|.|:|...:...|.|: ..|.|.....|:..:.......:..
 Worm   804 VGKQLRTIEALIEESDYLDIYQDFQRSLIMRLYESLDWD-EQGANPNQKRLQVDIFAVACRLQIK 867

  Fly   883 DTIEEAKIRFRRHVNGTELLPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALG 947
            |..::|..|:.:.|:.....|........:.|.| |:...:..:...|:......|::.|..||.
 Worm   868 DCTKQAYQRYLQWVSSGVRNPEHHMIALMEGVKQ-GETTAWERIWKAYKTATSPSEKNNIIGALT 931

  Fly   948 CCGDLKLLRRVIDFAMSSEVRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQG----GF 1008
            ...|..|:.|::.:.:..:::|.....|....::|...|::.|:|||.:    .|::.|    |.
 Worm   932 STKDASLINRLLKYCLDGKIKANLIPRVFSYFSLNQSTRNIVWKFFKTH----FEQFHGILGKGS 992

  Fly  1009 LLSRLIKYLIENFASEERAKEVEEFLQVNQI--PGCERTVSQAVETIRLNAAWLQRDREQL 1067
            |::..:|.|.|..::|...:||:|||:..:.  .|..: :....|.|.||..|.:.:..||
 Worm   993 LMASCVKCLAEPLSTETELEEVKEFLKSQKFAEDGLIK-MEMTYEQIELNIQWRKLNEGQL 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	151/450 (34%)
		ERAP1_C	741..1055	CDD:463368	70/321 (22%)
F49B2.6	NP_493503.2	M1_APN-Q_like	209..649	CDD:341064	151/449 (34%)
		ERAP1_C	725..1024	CDD:463368	67/304 (22%)