Protein Alignment Psa and Enpep

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_031960.1
• Gene: Enpep / 13809
• MGIID: 106645
• Length: 945
• Species: Mus musculus
• Alignment Length: 922
• Identity: 305/922 - (33%)
• Similarity: 481/922 - (52%)
• Gaps: 57/922 - (6%)

  Fly   173 DVIPGQDRHHPGCNYQQIRRAHTQLLSKEQQL--EQERKMAQKAKFERLPTNVVPRHYELLLQPN 235
            |..|...:..|        .|.|.|..::|.:  :.|.:..:...| |||..:.|.||:|.::..
Mouse    46 DTTPAPSQPPP--------EASTALPPQDQNVCPDSEDESGEWKNF-RLPDFINPVHYDLEVKAL 101

  Fly   236 LKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSV-ELHFECSKLKPEKIVYSAENETATLEFAQ 299
            ::|..:||...:.||:.:||..:.|:..:..:..: ||.....:..|.:..:..:.:...:..|.
Mouse   102 MEEDRYTGIVTISVNLSKPTRDLWLHIRETKITKLPELRRPSGEQVPIRRCFEYKKQEYVVIQAA 166

  Fly   300 EIPAETQG----VLHMSFTGELNDKMKGFYRSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPA 360
            |..|.|.|    .|.|.|.|.||..:.|||::.|. .:|:.|....|..|.||||:.|||:|||.
Mouse   167 EDLAATSGDSVYRLTMEFKGWLNGSLVGFYKTTYM-EDGQIRSIAATDHEPTDARKSFPCFDEPN 230

  Fly   361 IKATFDITLVVPKDRVALSNMPVIKEDSLPDGLRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDD 425
            .|:|:.|:::.||:..||||||..|.:.:.|..::..|.::..||||||...|..:..:|.||..
Mouse   231 KKSTYSISIIHPKEYSALSNMPEEKSEMVDDNWKKTTFVKSVPMSTYLVCFAVHRFTAIERKSRS 295

  Fly   426 GVLVRVFTPVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYR 490
            |..::|:....::|...:|..:...|..|::|||.:.|.|||:|.|||.||..||||||||||||
Mouse   296 GKPLKVYVQPNQKETAEYAANITQAVFDYFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYR 360

  Fly   491 ETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPE 555
            ||.:|.||..::...:|.:|..|.||:.||||||.|||:||..||||||:|||.|||.|:|...:
Mouse   361 ETNLLYDPLLSASSNQQRVASVVAHELVHQWFGNTVTMDWWDDLWLNEGFASFFEFLGVNHAEKD 425

  Fly   556 YDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTF 620
            :.:.:|.:.:......|.|||.:|||:.|.|..|:||..:||.|||:||||::|||.|:|..:.|
Mouse   426 WQMLSQVLLEDVFPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKF 490

  Fly   621 RKGMNLYLTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRL 685
            :||..:||.:.|:.|..|.|.|.:|||||:..|.:||.:||...|:|||:|...|....:|.|
Mouse   491 QKGCQIYLKKFQFANAKTSDFWDSLQEASNLPVKEVMDTWTSQMGYPVVTVSGRQNITQKRFL-- 553

  Fly   686 KQCKFTADGSQ--ADENCLWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLD-NVDEDDWIKINPG 747
              ....||.||  ::....|.:|:..:.:.| :.|.....|||..  :||: |:..|.::||||.
Mouse   554 --LDSKADPSQPPSELGYTWNIPVRWADNDN-SRITVYNRLDKGG--ITLNANLSGDAFLKINPD 613

  Fly   748 TVGYYRTRYSQEMLEQLMPAVEK--MELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNET 810
            .:|:||..|.....:.:..|:..  ......||...|||.||:.:|...:....|.|....::|.
Mouse   614 HIGFYRVNYEGGTWDWIAEALSSNHTRFSAADRSSFIDDAFALARAQLLNYKIALNLTMYLKSEE 678

  Fly   811 NYTVWTAITNSLTNLHILISHTDLMEDFHRFGRNLY-----------EPVAYRLGWEPRDGENHL 864
            ::..|..:.:|::   .:||   :.||    .|.||           :|||..|||:  |..:|:
Mouse   679 DFLPWERVISSVS---YIIS---MFED----DRELYPMIETYFQGQVKPVADLLGWQ--DTGSHI 731

  Fly   865 DTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNGTELLPADLRTTCYKAVLQD-GDEKIFNEMLD 928
            ..|||:.:|.........:.:..|...|...:.|:..:|.:||...|:..:|: |:|..:|..|:
Mouse   732 TKLLRASILGFACKMGDREALGNASQLFDSWLKGSASIPVNLRLLVYRYGMQNSGNEAAWNYTLE 796

  Fly   929 LYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSE-VRAQDSVFVIVAVAINPKGRDMAWEF 992
            .|:.|.|.:|::::...|....|:|||.|.::...... ::.||...||..::.|..|:.|||.:
Mouse   797 QYQKTSLAQEKEKLLYGLASVKDVKLLARYLEMLKDPNIIKTQDVFTVIRYISYNSYGKTMAWNW 861

  Fly   993 FKENNKQLLERYQ-GGFLLSRLIKYLIENFASEERAKEVEEFLQVNQIPGC-ERTVSQAVETIRL 1055
            .:.|...|:.|:. ....|.|::. :.|.|.:|.:..:::.|.......|. .:...|.:||::.
Mouse   862 IQLNWDYLVSRFTINDRYLGRIVT-IAEPFNTELQLWQMQSFFAKYPNAGAGAKPREQVLETVKN 925

  Fly  1056 NAAWLQRDREQL 1067
            |..||..:|:.:
Mouse   926 NIEWLNVNRQSI 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	179/439 (41%)
		ERAP1_C	741..1055	CDD:463368	85/330 (26%)
Enpep	NP_031960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..77		8/38 (21%)
		M1_APN-Q_like	92..531	CDD:341064	178/439 (41%)
		ERAP1_C	607..925	CDD:463368	85/330 (26%)