Protein Alignment Psa and lvrn

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: XP_031748993.1
• Gene: lvrn / 100496094
• XenbaseID: XB-GENE-980447
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 962
• Identity: 264/962 - (27%)
• Similarity: 446/962 - (46%)
• Gaps: 152/962 - (15%)

  Fly   218 RLPTNVVPRHYELLLQPNLKE-----FTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHFECS 277
            |||.|:||.||:|.|.|.::|     :.|:|:..:.::..|.|..:.|:::.:....|.|..
 Frog    71 RLPHNLVPLHYDLELWPRMEEDEEGNYPFSGQVNITISCVEDTDVVLLHSIQLNFSDVGLRL--- 132

  Fly   278 KLKPEKIVYSA----------------------------------------ENETATLEFAQEIP 302
             |..:.|:|.:                                        ::....||..:.:.
 Frog   133 -LGNKTIMYQSMEKDGKHNALQEGRAYKRLQDPTYDIHGGNVSINNVWTFEDHSYVVLELNERLV 196

  Fly   303 AETQGVLHMSFTGELNDKMKGFYRSKYFGPNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDI 367
            |....:|.:::||.:......|.  .::.....::....:..|...||..:||:||||:||||.|
 Frog   197 AGNLYLLELNYTGFIRQNTALFI--THYKDFNIDKAVVASLLEPEYARAVYPCFDEPALKATFKI 259

  Fly   368 TLVVPKDRVALSNMPVI----KEDSLPDG--LRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDG 426
            .||.....|||||||.:    :||.  ||  .....||.||.||||:.|.|:.::||| ..::.|
 Frog   260 RLVHNSSYVALSNMPAVAVSEREDI--DGSIWTVTTFDTTPKMSTYITAFVICDFDYV-NITERG 321

  Fly   427 VLVRVFT--PVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTY 489
            ..:||:.  .|.::...:.||.:|..:|.|.:|.||::|||.|.|.:|:.|....|||||||:|:
 Frog   322 NEIRVWARKEVVQKGFASLALSIAGPLLSYMEDLFNVSYPLQKTDFVALPDLDVEAMENWGLITF 386

  Fly   490 RETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEF-------- 546
            .|..::.||:..|...|...:|.|.||||||||||||||:|||.||||||:|:::|:
 Frog   387 IEEALIYDPRQKSSNSKFRTSLIVSHEIAHQWFGNLVTMKWWTDLWLNEGFATYMEYFGITFLDS 451

  Fly   547 -LCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRM 610
             |.::.||..:::...|..|:...|..: |:|.....|....|      :|:|.:|:||::::||
 Frog   452 KLELNELFTMHNLQPIFERDVGAHAKTV-SMKEEELYEADSSH------MFNEFTYDKGSALVRM 509

  Fly   611 LHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQ--------EASSKNVSDVMTSWTQHKGFP 667
            |..::.|..|.||::.||....:.|...:|||..||        ......:..:|.|||..:|.|
 Frog   510 LSSFLTEKLFIKGISSYLKTFSFSNVDQDDLWNHLQMFIDHQDEVRLPTTLRHIMQSWTWQRGIP 574

  Fly   668 VVSVESEQTSKNQRLLRLKQCKFTADGSQADENCLWVVPISVSTSKNPTGIAKTFLLDKSSMEVT 732
            ::::::......:.|.:..    ..|...:|.|..|:||  |:..||.|.....:|..||.:...
 Frog   575 LLTLDTTTGELAEELFKTD----NTDNITSDSNHTWIVP--VTWMKNGTKQISLWLDSKSKVFPV 633

  Fly   733 LDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAVE--KMELPPLDRLGLIDDMFAMVQAGHAS 795
            |... .|:||.:|....|||||.|::|...:|...:|  ...:|.::|:.||:|.|.:.:.|:..
 Frog   634 LTTA-ADEWIVLNINVTGYYRTNYNKENWNRLAKQLEANPKVVPTVNRIQLIEDAFILARYGYTD 697

  Fly   796 TADVLALVDSYRNETNYTVWTAITNSLTNL-HILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRD 859
            ....|:|......|....||..:...:|:. :.||::|: ...|.::......|:..|.....|.
 Frog   698 HGTALSLTKYLEKEEEINVWYTVLKHVTSSDYPLITYTN-FPLFKKYILKRISPIYQRFANSIRR 761

  Fly   860 G----------ENHLDTLLRSLVLTRLVSFRSSDTIEEAK---IRFRRHVNGTELLPADLRT--T 909
            .          :.|::     |:|....||...|.::.|.   ..:.::.:| .::|..:|.  .
 Frog   762 NFDEAADDYFIQVHIE-----LILKTACSFGLQDCLQLAHQLYATWMKNCSG-NVIPESIRNPIC 820

  Fly   910 CYKAVLQDGDE------KIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVR 968
            || |:...|::      |:.|:..::        |:|.:..||.|..:..||.|.:::::  |:.
 Frog   821 CY-AIANGGEKEWEFAWKMVNKSEEI--------ERDLLFYALSCTKEPWLLHRYLEYSL--EMY 874

  Fly   969 AQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQGGFLLSRLIKYLIENFASEERA----KE 1029
            ...:..:.:.|..|..||.:||||.|||.:::.:.: |..........|:..|||:..:    :|
 Frog   875 KSSAFTIFLDVIKNEIGRHIAWEFLKENWQRIHDIF-GPRDTVDFYTVLLPTFASKAASDLQFQE 938

  Fly  1030 VEEFLQVNQIPGCERTVSQAVE---------TIRLN---AAWLQRDREQLAI 1069
            ::.|:...........:.:.||         |.::|   ..||||:.::..|
 Frog   939 IQLFINTTINENQRERILEQVENKWRKSLGWTSKINDEILTWLQRNADEAEI 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	155/504 (31%)
		ERAP1_C	741..1055	CDD:463368	78/350 (22%)
lvrn	XP_031748993.1	M1_APN-Q_like	79..568	CDD:341064	154/504 (31%)
		ERAP1_C	641..945	CDD:463368	75/322 (23%)