Protein Alignment Psa and trhde.1

DIOPT Version :10

• Sequence 1: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: XP_001345457.3
• Gene: trhde.1 / 100006808
• ZFINID: ZDB-GENE-170406-2
• Length: 994
• Species: Danio rerio
• Alignment Length: 909
• Identity: 289/909 - (31%)
• Similarity: 469/909 - (51%)
• Gaps: 82/909 - (9%)

  Fly   218 RLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHFECSK---- 278
            |||..:.||||:|.|..:::.|:|:|:..::......|..|.|::..:.||.| |.|..||
Zfish   109 RLPATLRPRHYDLRLTVHMENFSFSGEVNIEFECVNSTKLIVLHSDRLELDKV-LVFSDSKKAGA 172

  Fly   279 LKPEKIVYSAENETATLEFAQEI-PAETQGVLHMSFTGELNDKMKGFYRSKYFGPNGEERFAGVT 342
            ::.::..:....:...:...:|: |..|..: :::||..:..::.||:||.|. .|||.||..||
Zfish   173 MRIQRRFHYQPKQVYVIALHREMKPLRTYKI-NITFTAHIEHELLGFFRSSYM-LNGERRFLAVT 235

  Fly   343 QFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDGLRRVRFDRTPIMSTY 407
            ||..|.||:.|||:|||..||||.::|.......:||||||....|..||.....|.|||.||||
Zfish   236 QFSPTHARKAFPCFDEPIYKATFRVSLKHESSYQSLSNMPVEATTSDEDGWVTNHFSRTPRMSTY 300

  Fly   408 LVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGT--FALEVATKVLPYYKDYFNIAYPLPKMDL 470
            .:|..|..:.|.|..:|:|||:|::......:.|:  :||.:..::|.:|:|||.:.|.|||:||
Zfish   301 YLAWAVCNFTYKEAVADNGVLIRLYARPDAIQSGSGDYALRITKRLLQFYQDYFKVKYSLPKLDL 365

  Fly   471 IAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLW 535
            :|:......|||||||..:.|..:|:||:.:|...:..:.:.|.|||.|||||:|||..||..:|
Zfish   366 LAVPKHPYSAMENWGLSVFVEQKILLDPEVSSFSYQMELTVVVVHEICHQWFGDLVTPVWWEDVW 430

  Fly   536 LNEGYASFVEFLCVHHLFPEYDIWTQ-FVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEI 599
            |.||:|.:.|::....|||::::..| |:||:....:.||.|.:||||...|...::||.:||.|
Zfish   431 LKEGFAHYFEYIGADFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPISQQVFEATDIDRVFDWI 495

  Fly   600 SYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSK-----NVSDVMTS 659
            :|.|||::||||.:.:|:..|::.:|.||..|.|||...:|||..|.||..:     |::.||..
Zfish   496 AYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSEAMQREGKDINITQVMDR 560

  Fly   660 WTQHKGFPVVSVESEQTSKNQRL---LRLKQCKFTADGSQADEN-------CLWVVPISVSTSKN 714
            ||...|:|||::     |||..|   :.:.|..|..|.....:|       ..|.:|::::.. |
Zfish   561 WTLQMGYPVVTI-----SKNDSLDNSITISQEHFVYDTDAKIQNPELFNKSFQWQIPLTLAVG-N 619

  Fly   715 PTGIAKTFLL---DKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYS----QEMLEQLM--PAVEK 770
            .:.|:...::   :||... .:.::..:.|:..|....||:|..|.    :.:::|||  |.:..
Zfish   620 ASHISTETIIWVTNKSEAH-RVGHMVGETWLLGNINQTGYFRVNYDLHNWKLLIQQLMSNPTIIS 683

  Fly   771 MELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHILISHTDLM 835
            :.    :|.|||||:|.:.:||:......|.::.....|..:..|.|.:.:|..|..|:..|...
Zfish   684 VG----NRAGLIDDVFNLARAGYLPQNVPLQMISYLSQEPEFLPWHAASRALYQLDKLLDRTLDH 744

  Fly   836 EDFHRFGRNLYEPVAYRLGWEPR--DGE-----NHLDTLLRSLVLTRLVSFRS-----------S 882
            ..|..:.....||..::|||...  ||.     ...:.|.|.:::. ..||.:           |
Zfish   745 SLFSDYVLRQVEPKYHKLGWPATSPDGSFMHSAYQTEELQREVIML-ACSFGNKHCHRQAVSLIS 808

  Fly   883 DTIEEAKIRFRRHVNGTELLPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALG 947
            |.|...|.|          :|.::|...|...:...||.::..:...:.::....|:..:..||.
Zfish   809 DWISSNKNR----------IPPNVRDIVYCTGVSLMDEDVWEFIWMKFHSSTAVSEKKVLLEALT 863

  Fly   948 CCGDLKLLRRVIDFAMSSE-VRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERY-QGGFLL 1010
            |..::.||.|:::.:::|: |..||.:.||:.||.||.||.:||.:|:|....|..|| :..|:.
Zfish   864 CSDNIFLLNRLLNLSLTSDLVPDQDVIDVIIHVARNPLGRHLAWRYFREKWDILNSRYGEALFMN 928

  Fly  1011 SRLIKYLIENFASEERAKEVEEFLQVNQIPGCER--TVSQAVETIRLNAAWLQRDREQLAIFLR 1072
            |:||..:.|...:|....|::||:..:   |.|.  ..::|||.::.|..|....:||...:||
Zfish   929 SKLISGVTEFLNTEAELNELKEFILTS---GGESAPAFARAVEIVQANVKWHILFQEQFYQWLR 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	170/447 (38%)
		ERAP1_C	741..1055	CDD:463368	89/341 (26%)
trhde.1	XP_001345457.3	M1_APN-Q_like	118..563	CDD:341064	170/447 (38%)
		ERAP1_C	648..975	CDD:463368	90/344 (26%)