DRSC/TRiP Functional Genomics Resources

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Protein Alignment cue and Lrp3

DIOPT Version :9

Sequence 1:NP_612113.2 Gene:cue / 38174 FlyBaseID:FBgn0011204 Length:644 Species:Drosophila melanogaster
Sequence 2:XP_038948896.1 Gene:Lrp3 / 89787 RGDID:619729 Length:810 Species:Rattus norvegicus


Alignment Length:274 Identity:61/274 - (22%)
Similarity:94/274 - (34%) Gaps:93/274 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   334 DHHCASIVRKVKERVDEQSRK-----FEIRSLLDQKIKVLE-----DERCMNDGEYRAATDLCIC 388
            |.||..:       ||.|..:     .|:|...|..::|.|     .:|.:....||:...    
  Rat   279 DLHCTWL-------VDTQDPRRVLLQLELRLGYDDYVQVYEGLGERGDRLLQTLSYRSNHR---- 332

  Fly   389 PTGFKGSRCEIRECHN----YCVHG---TCQMSELAYPKCYCQP-------------GFKGER-C 432
            |...:.::..:...::    ...||   |.|:      |.||.|             |..||: |
  Rat   333 PVSLEAAQGRLTVAYHARARSAGHGFNATYQV------KGYCLPWEQPCGSSSEGDDGSTGEQGC 391

  Fly   433 --ELSVCSGLCLNGGHCRVSKDENEAPSC---ECPAKFGGARCEQNSTEICSLFCRLLKHEPEMY 492
              |...|.|    ..||...:||...|:|   :.|.:.|...|...:..     |...|..|:..
  Rat   392 FSEPQRCDG----WWHCASGRDEQGCPACPPDQYPCEGGSGLCYAPADR-----CNNQKSCPDGA 447

  Fly   493 VPFGCHS-----------IC---------EELAQDNSTNIAIPQYQHLEVCLTPR-VWTSSVIII 536
            ....|.|           :|         :|..||.|.       :|..:...|| |.|:::|..
  Rat   448 DEKNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSD-------EHGCLAAVPRKVITAALIGS 505

  Fly   537 LVVGIVSSLLLVAV 550
            ||.|:   ||::|:
  Rat   506 LVCGL---LLVIAL 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cueNP_612113.2 LY 101..141 CDD:214531
Ldl_recept_b 167..208 CDD:278487
LY 193..237 CDD:214531
Lrp3XP_038948896.1 CUB 43..156 CDD:238001
LDLa 166..200 CDD:238060
LDLa 212..249 CDD:238060
CUB 254..364 CDD:238001 18/95 (19%)
LDLa 416..452 CDD:238060 7/40 (18%)
LDLa 455..489 CDD:238060 6/40 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1215
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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