DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cue and Lrp10

DIOPT Version :9

Sequence 1:NP_612113.2 Gene:cue / 38174 FlyBaseID:FBgn0011204 Length:644 Species:Drosophila melanogaster
Sequence 2:NP_075369.2 Gene:Lrp10 / 65107 MGIID:1929480 Length:713 Species:Mus musculus


Alignment Length:279 Identity:68/279 - (24%)
Similarity:94/279 - (33%) Gaps:97/279 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   369 EDERCMNDGEYRAA--TDLCICP-----------TGFKGS--------RCEIRECHNYCVHGTCQ 412
            |.:||  ||.:..|  ||...||           .|..|:        ||..:   .:|..|..:
Mouse   335 EAQRC--DGSWDCADGTDEEGCPGCPPGHFPCGAAGTPGATACYLPADRCNYQ---TFCADGADE 394

  Fly   413 MSELAYPKC-YCQPG---FKGERC--ELSVCSGL--CLNGGHCRVSKDENEAPSCECPAKFGGAR 469
            .      :| :||||   .:.|:|  |..||.|.  |.:|             |.|....:...|
Mouse   395 R------RCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDG-------------SDEWDCSYALPR 440

  Fly   470 CEQNSTEICSLFCRLLKHEPEMYVPFGC-----------HSICEELAQDNSTNI---AIPQYQHL 520
            ....:..|.||.|.||     :.:..||           :||...|::..:..:   |.|.|..|
Mouse   441 KVITAAVIGSLVCGLL-----LVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQL 500

  Fly   521 ---------EVCLTPRVWTSSVIIILVVGIVSSLLLVAVIVQGIRRLYKP-----KRPRIRKTFV 571
                     |...|.....:||:     |.:.|||      |.:|:...|     .|.|.|...:
Mouse   501 IAQGAIPPVEDFPTENPNDNSVL-----GNLRSLL------QILRQDMTPGGTSGGRRRQRGRSI 554

  Fly   572 VRKQARTNSAGDTPLTNRP 590
            .|...|....|..|.||.|
Mouse   555 RRLVRRLRRWGLLPRTNTP 573

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cueNP_612113.2 LY 101..141 CDD:214531
Ldl_recept_b 167..208 CDD:278487
LY 193..237 CDD:214531
Lrp10NP_075369.2 CUB 35..135 CDD:238001
LDLa 141..175 CDD:238060
CUB 193..303 CDD:238001
LDLa <331..354 CDD:238060 8/20 (40%)
LDLa 400..434 CDD:238060 14/46 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 566..636 4/8 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1215
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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