Protein Alignment cue and lrp5

DIOPT Version :10

• Sequence 1: NP_612113.2
• Gene: cue / 38174
• FlyBaseID: FBgn0011204
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001170929.3
• Gene: lrp5 / 568518
• ZFINID: ZDB-GENE-050518-2
• Length: 1615
• Species: Danio rerio
• Alignment Length: 270
• Identity: 82/270 - (30%)
• Similarity: 138/270 - (51%)
• Gaps: 23/270 - (8%)

  Fly     8 MDVLLVLLLATCLLTPAHGTPLEWDFAVTLRTKIQFMDSSWQTIATAAHEFDELSALTFDESEEL 72
            |::||:.||..|.||...|:||.. ||.....::..::......|....:.::.:|:.|..||.|
Zfish    10 MEILLLELLLCCSLTVIRGSPLLL-FANRRDVRLVDVEVGRSESAVVVSDLEDAAAVDFLFSEGL 73

  Fly    73 IYFNDLK-------HRNGSIFSLKRDLIAANHVAEQTIARTGNESVGGLAYDPLNMNLFWSDTEQ 130
            |::.|:.       :.|.|..|:|...:...    ||:..:|.:|..|||.|.|...|:|:|:|.
Zfish    74 IFWTDVSEEAIKQTYYNLSTNSMKEATLGKG----QTVVVSGLDSPDGLACDWLGHKLYWTDSET 134

  Fly   131 RKIFFAPIHGSATPQVLV--DLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTV 193
            .:|..|.:.|::. :||.  ||.    :|..:|::...|.:|||:.. ..|.:||..:|||||.:
Zfish   135 NRIEVANLDGTSR-KVLFWQDLD----QPRAIALNPSHRYMYWTDWG-EEPRIERAGMDGSNRQI 193

  Fly   194 IISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDAI 258
            |:...|..|.|:.:|....:|:|. |.|..|  :..:.|||:.|:.|::.....|..|.:.::.:
Zfish   194 IVQKQIYWPNGLTIDLDEQKLYWA-DAKLSF--IHRANLDGTSREAVVEGSLTHPFALTLYDETL 255

  Fly   259 YWTDRTTRAV 268
            ||||..||::
Zfish   256 YWTDWQTRSI 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cue	NP_612113.2	TerD_like	48..>85	CDD:473128	9/43 (21%)
		YvrE	<73..>164	CDD:442613	28/99 (28%)
		LY	101..141	CDD:214531	15/39 (38%)
		Ldl_recept_b	167..208	CDD:459654	16/40 (40%)
		LY	193..237	CDD:214531	13/43 (30%)
lrp5	NP_001170929.3	None