Protein Alignment cue and lrp1aa

DIOPT Version :10

• Sequence 1: NP_612113.2
• Gene: cue / 38174
• FlyBaseID: FBgn0011204
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_073772278.1
• Gene: lrp1aa / 563149
• ZFINID: ZDB-GENE-030131-7889
• Length: 4578
• Species: Danio rerio
• Alignment Length: 602
• Identity: 150/602 - (24%)
• Similarity: 229/602 - (38%)
• Gaps: 162/602 - (26%)

  Fly    95 ANHVAEQTIART------GNESVGGLAYDPLNMNLFWSDTEQRKIFFAPIHGSATPQVLVDLSAE 153
            :|....||..|.      |.:...|:|.|.:..|::|:|:.:..|..|.::|.....::..:..|
Zfish  3957 SNRNRRQTDPRVTDLEIPGLKMPRGIAVDWVANNIYWTDSGRDVIEVAQMNGRNRKTLISGMIDE 4021

  Fly   154 GGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPRGIVVDQLSDRLFWID 218
               |..:.||..|..:||.:.. .||.:|...:||:.|..::..||..|.|:.||..::||:|.|
Zfish  4022 ---PYAIVVDPQRGTMYWADWG-NHPKIETAAMDGTLRETLVHDNIQWPTGLAVDYFNERLYWAD 4082

  Fly   219 DLKGVFFSVESSKLDGSDRQVV---LKDKHHEPLNLAVTNDAIYWTDRTTRAVWSHPKVPVIKVT 280
            ....|..||   :|:|:|..:.   :|:...:|.::.:..|.||       .|..|... |.:|.
Zfish  4083 AKLSVIGSV---RLNGTDPVIAVSSIKNNLQQPFSIDIFEDFIY-------GVTYHNNF-VFRVN 4136

  Fly   281 TTSKPDEEDST----DSTD------FKDPEPVAEDCPLVR---VANLSEEARGIVARTGFYQRLQ 332
            ...|...|..|    .:||      :|.|| :|..|...:   :..||..........|   |:.
Zfish  4137 KFGKSSVEHLTTGMNHATDLVLYHPYKQPE-MANPCDRKKCEWLCLLSPSGPVCTCPNG---RIL 4197

  Fly   333 KDHHCASIVRKVKERVDEQSRKFEIRSLLDQKIKVLEDERCMNDGE-YRAATDL--CICPTGFKG 394
            .:..|..|.......|....    ..:||           |:|.|. ...|..|  |.|...:.|
Zfish  4198 DNGTCVEIPAPTLSPVSPSG----TCNLL-----------CLNGGTCVLNARKLPKCRCQPNYGG 4247

  Fly   395 SRCEIRECHNYCVH-GTCQMSELAYPKCYCQPGFKGERCELSVCSGLCLNGGHCRVSKDENEAPS 458
            .|||:.:|..||.: |||..|....|.|.|..||.|..|....|...|.:||:|.||:  ...|:
Zfish  4248 ERCELNQCRGYCQNGGTCTASPTGAPTCRCLAGFTGPNCNQRTCENYCKSGGNCTVSR--GNQPT 4310

  Fly   459 CECPAKFGGARCEQ-------------------------------NSTEI--CSLFCRLLKHEP- 489
            |.|||.|.|.:|:.                               |:.|:  |. :||..|..|
Zfish  4311 CSCPADFLGDQCQYRTCDGFCDHGGTCLQSSDGSRQCRCPPRFIGNNCEVDKCH-YCRDGKCIPI 4374

  Fly   490 EMYVPFG--------------CHSICEELAQD-----NSTNIAIPQYQHLEVCLTPRVW------ 529
            .:|.|.|              |:: ||....:     .|||  :||      |..|..|
Zfish  4375 NIYQPKGDVTCRCTSGRIQPSCYT-CEGYCANGQCSLGSTN--LPQ------CKCPLGWEGHRCE 4430

  Fly   530 -------------TSSVIIILVVGIVSSLLLVAVIVQGIRRLY----------KPKRPRIRKTFV 571
                         |:|::|.:::     |:|:.:::.|....|          :.|||| .|.|
Zfish  4431 NPARNENAESSGRTASIVIPVIL-----LILLVLLIGGAALWYRKRMRGLGKSRSKRPR-AKGF- 4488

  Fly   572 VRKQARTNSAGDTPLTN 588
             :.|..||.|.:..:.|
Zfish  4489 -QHQRMTNGAMNVEIGN 4504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cue	NP_612113.2	TerD_like	48..>85	CDD:473128
		YvrE	<73..>164	CDD:442613	17/74 (23%)
		LY	101..141	CDD:214531	12/45 (27%)
		Ldl_recept_b	167..208	CDD:459654	12/40 (30%)
		LY	193..237	CDD:214531	15/43 (35%)
lrp1aa	XP_073772278.1	None