DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cue and Ser

DIOPT Version :9

Sequence 1:	NP_612113.2	Gene:	cue / 38174	FlyBaseID:	FBgn0011204	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001287558.1	Gene:	Ser / 43275	FlyBaseID:	FBgn0004197	Length:	1407	Species:	Drosophila melanogaster

Alignment Length:	151	Identity:	46/151 - (30%)
Similarity:	64/151 - (42%)	Gaps:	28/151 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 CMNDGEYR--AATDLCICPTGFKGSRC--EIRECHNYCVHGTCQMSELAYPKCYCQPGFKGERCE 433
            |:|..|.|  ..:..|||..|:.|..|  .:.:|...|.:|...:..:...:|.|..||||..||
  Fly   581 CINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCE 645

  Fly   434 LSV---CSGLCLNGGHC--RVSKDENEAPSCECPAKFGGARCEQNSTEICSLFCRLLKH---EPE 490
            ..:   .:..|.|||.|  .|.|.     :|.||..:.|:.||: :.|.|:....|..|   .||
  Fly   646 TDIDECATSPCRNGGECVDMVGKF-----NCICPLGYSGSLCEE-AKENCTPSPCLEGHCLNTPE 704

  Fly   491 MYVPFGCH-------SICEEL 504
            .|.   ||       ..||:|
  Fly   705 GYY---CHCPPDRAGKHCEQL 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cue	NP_612113.2	LY	101..141	CDD:214531
		Ldl_recept_b	167..208	CDD:278487
		LY	193..237	CDD:214531
Ser	NP_001287558.1	MNNL	83..161	CDD:284966
		DSL	220..282	CDD:279722
		EGF_CA	350..388	CDD:238011
		EGF_CA	490..526	CDD:238011
		EGF_CA	610..645	CDD:238011	9/34 (26%)
		EGF_CA	647..683	CDD:238011	11/40 (28%)
		EGF_CA	798..833	CDD:238011
		EGF_CA	879..913	CDD:238011
		EGF_CA	916..952	CDD:238011
		VWC_out	<993..1053	CDD:214565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24044
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100