| Sequence 1: | NP_612113.2 | Gene: | cue / 38174 | FlyBaseID: | FBgn0011204 | Length: | 644 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011543331.1 | Gene: | LRP5 / 4041 | HGNCID: | 6697 | Length: | 1662 | Species: | Homo sapiens |
| Alignment Length: | 426 | Identity: | 102/426 - (23%) |
|---|---|---|---|
| Similarity: | 164/426 - (38%) | Gaps: | 133/426 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 38 RTKIQFMDSSW----QTIATAAHEFDELSALTFDESEELIYFNDLKHRNGSIFSLKRDLIAANHV 98
Fly 99 AEQTIARTGNESVGGLAYDPLNMNLFWSDTEQRKIFFAPIHGSATPQVLV--DLSAEGGRPDGVA 161
Fly 162 VDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFS 226
Fly 227 VESSKLDGSDRQVVLKDKHHEPLNLAVTNDAIYWTDRTTRAVWSHPKVPVIKVTTTSKPDEEDST 291
Fly 292 DSTDFKDPEPVAEDCPLVRVANLSEEARGIVARTGFYQRLQKDHHCASIVRKVKERVDEQSRKFE 356
Fly 357 IRSLL--DQKIKVLEDERCMNDGEYRAATDLCICPTGFKGSRCEIRECHNYCVHGTCQM--SELA 417
Fly 418 YPKCYCQPGFKGERCELSVCSGLCLNGGHCRVSKDE 453 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| cue | NP_612113.2 | LY | 101..141 | CDD:214531 | 13/39 (33%) |
| Ldl_recept_b | 167..208 | CDD:278487 | 16/40 (40%) | ||
| LY | 193..237 | CDD:214531 | 15/43 (35%) | ||
| LRP5 | XP_011543331.1 | NHL | <46..>178 | CDD:302697 | 34/140 (24%) |
| NHL repeat | 74..113 | CDD:271320 | 8/43 (19%) | ||
| LY | 111..151 | CDD:214531 | 13/39 (33%) | ||
| NHL repeat | 116..157 | CDD:271320 | 14/41 (34%) | ||
| Ldl_recept_b | 172..212 | CDD:278487 | 16/40 (40%) | ||
| LY | 196..238 | CDD:214531 | 15/44 (34%) | ||
| FXa_inhibition | 308..345 | CDD:291342 | 15/51 (29%) | ||
| LY | 375..415 | CDD:214531 | |||
| LY | 417..459 | CDD:214531 | |||
| LY | 460..503 | CDD:214531 | |||
| LY | 504..546 | CDD:214531 | |||
| LY | 547..580 | CDD:214531 | |||
| FXa_inhibition | 614..649 | CDD:291342 | |||
| NHL | 694..887 | CDD:302697 | |||
| LY | 719..761 | CDD:214531 | |||
| NHL repeat | 729..765 | CDD:271320 | |||
| NHL repeat | 772..811 | CDD:271320 | |||
| NHL repeat | 856..880 | CDD:271320 | |||
| FXa_inhibition | 915..950 | CDD:291342 | |||
| LY | 979..1018 | CDD:214531 | |||
| LY | 1069..1112 | CDD:214531 | |||
| LY | 1113..1155 | CDD:214531 | |||
| FXa_inhibition | 1226..1262 | CDD:291342 | |||
| Ldl_recept_a | 1267..1304 | CDD:278486 | |||
| LDLa | 1307..1341 | CDD:238060 | |||
| LDLa | 1345..1379 | CDD:238060 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1215 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||