Protein Alignment cue and Lrp12

DIOPT Version :10

• Sequence 1: NP_612113.2
• Gene: cue / 38174
• FlyBaseID: FBgn0011204
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001128355.1
• Gene: Lrp12 / 314941
• RGDID: 1304943
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 249
• Identity: 50/249 - (20%)
• Similarity: 87/249 - (34%)
• Gaps: 77/249 - (30%)

  Fly   369 EDERCMNDGEYRAATDLCICPTGFKGSRCEIRECHNYCVHGTCQMSELAYPKCYCQPGFKGERCE 433
            |.:||  ||.:.       ||.|.....|.:.:...:    .|..:.:.||        :.:||.
  Rat   391 EQQRC--DGYWH-------CPNGRDEINCTMCQKEEF----PCSRNGVCYP--------RSDRCN 434

  Fly   434 LSVCSGLCLNGGHCRVSKDENEAPSCECPAKFGGARCEQNSTEICSLFCRLLKHEPEMYVPFGCH 498
            ..         .||....||.....|: |..|   .|:.|.....|..|             ...
  Rat   435 YQ---------NHCPNGSDEKNCFFCQ-PGNF---HCKNNRCVFESWVC-------------DSQ 473

  Fly   499 SICEELAQDNSTNIAIPQYQHLEVCLTPRVWTSSVIIILVVGIVSSLLLVAV--------IVQGI 555
            ..|.:.:.:.|..:.:|          .||.|::||..||.|:   ||::|:        :....
  Rat   474 DDCGDGSDEESCPVIVP----------TRVITAAVIGSLVCGL---LLVIALGCTCKLYSLRMFE 525

  Fly   556 RRLYKPKRPRIRKTFVVRKQARTNSAGD-------TPLTNRPLATEQCEITIEN 602
            ||.::.:..|: :..::|::| ..|.|.       .|:.:.|:.:......:||
  Rat   526 RRSFETQLSRV-EAELLRREA-PPSYGQLIAQGLIPPVEDFPVCSPNQASVLEN 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cue	NP_612113.2	TerD_like	48..>85	CDD:473128
		YvrE	<73..>164	CDD:442613
		LY	101..141	CDD:214531
		Ldl_recept_b	167..208	CDD:459654
		LY	193..237	CDD:214531
Lrp12	NP_001128355.1	CUB	47..158	CDD:238001
		LDLa	166..200	CDD:238060
		LDLa	215..254	CDD:238060
		CUB	267..371	CDD:238001
		LDLa	413..448	CDD:238060	9/55 (16%)
		LDLa	451..485	CDD:238060	8/50 (16%)