DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cue and lrp5

DIOPT Version :9

Sequence 1:NP_612113.2 Gene:cue / 38174 FlyBaseID:FBgn0011204 Length:644 Species:Drosophila melanogaster
Sequence 2:XP_002941689.1 Gene:lrp5 / 100491803 XenbaseID:XB-GENE-485117 Length:1603 Species:Xenopus tropicalis


Alignment Length:260 Identity:78/260 - (30%)
Similarity:130/260 - (50%) Gaps:25/260 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 LLLATCLLTPAHGTPLEWDFAVTLRTKIQFMDSSWQTI--ATAAHEFDELSALTFDESEELIYFN 76
            ||...||.: :.|:||   .....|..::.:|:....:  .......::.:|:.|..|:.:||:.
 Frog     9 LLFCYCLAS-SWGSPL---LLFANRRDVRLVDAGGTKLESVVVVSGLEDAAAVDFLYSQGVIYWT 69

  Fly    77 DLKHRNGSIFSLKRDLIAANHVAE-QTIARTGNESVGGLAYDPLNMNLFWSDTEQRKIFFAPIHG 140
            |:...     |:|:.|.  |..:. ||:..:|..|..|||.|.:...|:|:|:|..:|....::|
 Frog    70 DVSEE-----SIKQTLY--NQSSNLQTVVISGLVSPDGLACDWIGKKLYWTDSETNRIEVGNLNG 127

  Fly   141 SATPQVLV--DLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPR 203
            :.. :||.  ||.    :|..:|:|.....:|||:...| |.:||..:|||.|.||:.::|..|.
 Frog   128 TYR-KVLFWQDLD----QPRAIALDPAHGYMYWTDWGDT-PRIERAGMDGSMRKVIVDTDIYWPN 186

  Fly   204 GIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDAIYWTDRTTRAV 268
            |:.:|....:|:|. |.|..|  :..:.||||.||.|::.....|..|.:..|.:||||..||::
 Frog   187 GLTIDLDEQKLYWA-DAKLSF--IHRANLDGSFRQKVVEGSLTHPFALTLAGDTLYWTDWQTRSI 248

  Fly   269  268
             Frog   249  248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cueNP_612113.2 LY 101..141 CDD:214531 13/39 (33%)
Ldl_recept_b 167..208 CDD:278487 16/40 (40%)
LY 193..237 CDD:214531 15/43 (35%)
lrp5XP_002941689.1 LY 88..130 CDD:214531 14/41 (34%)
LY 131..174 CDD:214531 17/47 (36%)
LY 175..217 CDD:214531 15/44 (34%)
LY 218..252 CDD:214531 11/31 (35%)
FXa_inhibition 287..324 CDD:373209
LY 354..394 CDD:214531
LY 396..438 CDD:214531
LY 439..482 CDD:214531
LY 484..525 CDD:214531
LY 526..559 CDD:214531
FXa_inhibition 593..628 CDD:373209
LY 657..697 CDD:214531
LY 698..740 CDD:214531
LY 741..783 CDD:214531
LY 785..826 CDD:214531
LY 826..867 CDD:214531
FXa_inhibition 894..929 CDD:373209
LY 958..998 CDD:214531
LY 1050..1093 CDD:214531
LY 1094..1136 CDD:214531
FXa_inhibition 1207..1243 CDD:373209
LDLa 1249..1285 CDD:238060
LDLa 1288..1322 CDD:238060
LDLa 1326..1360 CDD:238060
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.