Protein Alignment hfp and puf60a

DIOPT Version :9

• Sequence 1: NP_525123.2
• Gene: hfp / 38173
• FlyBaseID: FBgn0028577
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_005163557.1
• Gene: puf60a / 562370
• ZFINID: ZDB-GENE-030131-2891
• Length: 552
• Species: Danio rerio
• Alignment Length: 621
• Identity: 306/621 - (49%)
• Similarity: 375/621 - (60%)
• Gaps: 131/621 - (21%)

  Fly    59 GPGTRSALLGLLGGALPKLSSEQHDLVSKAKKYAMEQSIKMVLMKQTLAHQQQQLAT-------- 115
            |..|.|.|      .||.|:.||.:.:.||||||||||||.||:|||:|||||||..
Zfish    19 GQSTASKL------GLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMPNSLQ 77

  Fly   116 ---------------QRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPIKSINMSWDP 165
                           |....|||:|||:|||||||||.:||.|||||.||.||||||||:||||.
Zfish    78 MASLTMGFGDPLSPLQSVAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDS 142

  Fly   166 ITQKHKGFAFVEYEIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVIDEVQEEAKSFNRIY 230
            :|.|||||||||||:||.|||||||||..::||||||||||||:.|||.:||::.|||::|||||
Zfish   143 VTLKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIY 207

  Fly   231 VASIHPDLSEEDIKSVFEAFGPILYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGG 295
            |||:|||||::||||||||||.|..|.||:..:...|||||||||...|:..:|::|||||||||
Zfish   208 VASVHPDLSDDDIKSVFEAFGRIKSCSLARDPTTGKHKGYGFIEYDKAQSAQDAVSSMNLFDLGG 272

  Fly   296 QLLRVGRSITPPNALACPTTNSTMPTAAAVAAAAATAKIQA-------------------LDAVA 341
            |.||||:::|||..|..|.|...:|.|||||||||||||.|                   |:|||
Zfish   273 QYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQMAWNLSQPENRTEDFLNCLEAVA 337

  Fly   342 SNAVLGLSQNTPVMAAGAVVTKVGAMPVVSAATSAAALHPALAQAAPALLPPGIFQAPTPVAPSL 406
            ..::||      .|.||..::.                 |.|.||..|...||:....||..|::
Zfish   338 GASILG------AMTAGTGLSM-----------------PQLPQAVMAAQAPGVITGVTPARPAM 379

  Fly   407 LGVP-AGLQPLQAVVPTLPPPALLATPTLPMTVGGVGVGLVPTVATLAGAEASKGAAAAAALSAA 470
            ..|| .||     |.|.|..|     |||
Zfish   380 PVVPQVGL-----VNPVLSSP-----PTL------------------------------------ 398

  Fly   471 ANNAAVTAANLSENIKKAHEKQQEELQKKLMDEGDVQTLQQQENMSIKGQSARQLVMQRLMRPVD 535
              :|||.||   :..||  ||::||   .|:|....:.|.:||:|||.|.|||.:|||:|:|..:
Zfish   399 --SAAVAAA---QEAKK--EKEEEE---ALLDGLGQEMLSEQEHMSISGSSARHMVMQKLLRKQE 453

  Fly   536 SRVIILRNMVGPEDVDETLQEEIQEECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVEFSAG 600
            |.|::|||||||||:|:.|:.|:.|||.|||.|:||||:.|||.|.||   ||:||||||||||.
Zfish   454 STVMVLRNMVGPEDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEED---AEVIVKIFVEFSAA 515

  Fly   601 AEAMRGKEALDGRFFGGRRVVAELYDQGIFDQGDLS 636
            :|..:..:||:.|:||||:|:||:|||..||..|||
Zfish   516 SEMNKAIQALNNRWFGGRKVIAEVYDQERFDNSDLS 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hfp	NP_525123.2	half-pint	10..637	CDD:130706	306/621 (49%)
		RRM1_PUF60	130..205	CDD:240816	59/74 (80%)
		RRM2_PUF60	227..303	CDD:240817	51/75 (68%)
		RRM3_UHM_PUF60	536..636	CDD:241092	60/99 (61%)
puf60a	XP_005163557.1	half-pint	16..552	CDD:130706	306/621 (49%)
		P-loop_NTPase	<34..>131	CDD:304359	52/96 (54%)
		RRM1_PUF60	107..182	CDD:240816	59/74 (80%)
		RRM2_PUF60	204..280	CDD:240817	51/75 (68%)
		RRM3_UHM_PUF60	454..551	CDD:241092	60/99 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594789
Domainoid	1	1.000	200	1.000	Domainoid score	I2988
eggNOG	1	0.900	-	-		E1_KOG0124
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8614
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1296
OMA	1	1.010	-	-		QHG51929
OrthoDB	1	1.010	-	-		D438205at33208
OrthoFinder	1	1.000	-	-		FOG0005543
OrthoInspector	1	1.000	-	-		otm25887
orthoMCL	1	0.900	-	-		OOG6_104067
Panther	1	1.100	-	-	LDO	PTHR47330
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4280
SonicParanoid	1	1.000	-	-		X3961
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800