DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hfp and mod

DIOPT Version :9

Sequence 1:	NP_525123.2	Gene:	hfp / 38173	FlyBaseID:	FBgn0028577	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	72/376 - (19%)
Similarity:	134/376 - (35%)	Gaps:	110/376 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGSNDRASRSPRSDDQREIS-DMPATKRT-RSDSGKSTDS---------KIP------------- 41
            :..::.|.....|||..|.. :.|.:|:: :::|.||.::         |||
  Fly   117 VSKSEGADEVDESDDDEEAPVEKPVSKKSEKANSEKSEENRGIPKVKVGKIPLGTPKNQIVFVTN 181

  Fly    42 ----YLSQPLYDLKQTGDVKFG-----------PGTRSALLGLLGGALPKLSSEQHDLVSKAKKY 91
                ||.:.|..|    ..|||           .|.:|.|:..       .:|...:.|.:||..
  Fly   182 LPNEYLHKDLVAL----FAKFGRLSALQRFTNLNGNKSVLIAF-------DTSTGAEAVLQAKPK 235

  Fly    92 AMEQSIKMVLMKQTLAHQQQQLATQRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPI 156
            |:           ||......::..|.:.:..:.     .|.||.|...:.:|.::..|....|:
  Fly   236 AL-----------TLGDNVLSVSQPRNKEENNER-----TVVVGLIGPNITKDDLKTFFEKVAPV 284

  Fly   157 KSINMSWDPITQKHKGFAFVEY----EIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVID 217
            :::.:|.:.:..:    |||..    :||:..:|...::....:..|.|.....|...:...|::
  Fly   285 EAVTISSNRLMPR----AFVRLASVDDIPKALKLHSTELFSRFITVRRISQESISRTSELTLVVE 345

  Fly   218 EVQEEAKSFNRIYVASIHPDLSEEDIKSVFEAFGPI----LYCKLAQGTSLHTHKGYGFIEYANK 278
            .|.:             |...|.:.::.:|:.||.:    :.|..|.         ..|:.:...
  Fly   346 NVGK-------------HESYSSDALEKIFKKFGDVEEIDVVCSKAV---------LAFVTFKQS 388

  Fly   279 QAMDEAIA-----SMNLFDLGGQLLRVGRSITPPNALACPTTNSTMPTAAA 324
            .|..:|:|     ::|.|:  .:|.|..||   .:..|...||.|.....|
  Fly   389 DAATKALAQLDGKTVNKFE--WKLHRFERS---TSGRAILVTNLTSDATEA 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hfp	NP_525123.2	half-pint	10..637	CDD:130706	71/367 (19%)
		RRM1_PUF60	130..205	CDD:240816	16/78 (21%)
		RRM2_PUF60	227..303	CDD:240817	15/84 (18%)
		RRM3_UHM_PUF60	536..636	CDD:241092
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	17/88 (19%)
		RRM_SF	260..327	CDD:240668	14/70 (20%)
		RRM_SF	342..411	CDD:240668	15/92 (16%)
		RRM_SF	422..>465	CDD:302621	4/13 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930