Protein Alignment hfp and puf60b

DIOPT Version :9

• Sequence 1: NP_525123.2
• Gene: hfp / 38173
• FlyBaseID: FBgn0028577
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_009301670.1
• Gene: puf60b / 415211
• ZFINID: ZDB-GENE-040625-116
• Length: 520
• Species: Danio rerio
• Alignment Length: 600
• Identity: 280/600 - (46%)
• Similarity: 359/600 - (59%)
• Gaps: 107/600 - (17%)

  Fly    59 GPGTRSALLGLLGGALPKLSSEQHDLVSKAKKYAMEQSIKMVLMKQTLAHQQQQL---------- 113
            |.||.|.|      .||.|:.||.:.:.||||||||||||.||:|||:|||||||
Zfish     5 GQGTGSKL------GLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTM 63

  Fly   114 -------ATQRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPIKSINMSWDPITQKHK 171
                   :.|....|||:|||:|||||||||.:||.|||||.||.||||||||:||||.:|.|||
Zfish    64 GFGDPLSSLQSVAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHK 128

  Fly   172 GFAFVEYEIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVIDEVQEEAKSFNRIYVASIHP 236
            ||||||||:||.|||||||||..::||||||||||.::.|||.:|:::.|||:::||||||||||
Zfish   129 GFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPGSIGQAQPIIEQLAEEARAYNRIYVASIHP 193

  Fly   237 DLSEEDIKSVFEAFGPILYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGGQLLRVG 301
            |||::||||||||||.|..|.||:..:...|||:|||||...|:..:|::||||||||||.||||
Zfish   194 DLSDDDIKSVFEAFGKIKSCMLAREPTTGKHKGFGFIEYEKPQSSLDAVSSMNLFDLGGQYLRVG 258

  Fly   302 RSITPPNALACPTTNSTMPTAAAVAAAAATAKIQALDAVASNAVLGLSQNTPVMAAGAVVTKVGA 366
            :::|||..|..|||...:|.|||||||||||||.|.:|||...:..|:....:::     .::|
Zfish   259 KAVTPPMPLLTPTTPGGLPPAAAVAAAAATAKITAQEAVAGTVLSSLASPAHILS-----QQMG- 317

  Fly   367 MPVVSAATSAAALHPALAQAAPALLPPGIFQAPTPVAPSLLGVP-AGLQPLQAVVPTLPPPALLA 430
                            |.||..|...|||....||..|:|..|| .||.......|.:..||.:.
Zfish   318 ----------------LPQAVLAAQAPGIITGVTPARPTLPVVPQVGLVNPVLASPPVTAPASMG 366

  Fly   431 TPTLPMTVGGVGVGLVPTVATLAGAEASKGAAAAAALSAAANNAAVTAANLSENIKKAHEKQQEE 495
            |||                                           :|..|...:|:     :|:
Zfish   367 TPT-------------------------------------------SAVQLHTEVKR-----EED 383

  Fly   496 LQKKLMDE----GDVQTLQQQENMSIKGQSARQLVMQRLMRPVDSRVIILRNMVGPEDVDETLQE 556
            .::...|.    |:.|. .:.|.:|:...:.||..:|.     .|.|::|||||||||:|:.|:.
Zfish   384 SRRTAEDHSAPVGNGQD-SELERLSVSASAGRQAAIQS-----KSTVMVLRNMVGPEDIDDDLEG 442

  Fly   557 EIQEECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVEFSAGAEAMRGKEALDGRFFGGRRVV 621
            |:.|||.|:|.|:||||:.|:|.|   :|:||||||||||||...|..:..:||:.|:|.||:||
Zfish   443 EVMEECGKYGAVNRVIIYQERQGE---EDDAEIIVKIFVEFSDAGEMNKAIQALNNRWFAGRKVV 504

  Fly   622 AELYDQGIFDQGDLS 636
            ||||||..|:..||:
Zfish   505 AELYDQDRFNSSDLT 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hfp	NP_525123.2	half-pint	10..637	CDD:130706	280/599 (47%)
		RRM1_PUF60	130..205	CDD:240816	59/74 (80%)
		RRM2_PUF60	227..303	CDD:240817	51/75 (68%)
		RRM3_UHM_PUF60	536..636	CDD:241092	57/99 (58%)
puf60b	XP_009301670.1	half-pint	2..520	CDD:130706	280/599 (47%)
		P-loop_NTPase	<20..>111	CDD:304359	52/90 (58%)
		RRM1_PUF60	87..162	CDD:240816	59/74 (80%)
		RRM2_PUF60	184..260	CDD:240817	51/75 (68%)
		RRM3_UHM_PUF60	422..519	CDD:241092	57/99 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594790
Domainoid	1	1.000	200	1.000	Domainoid score	I2988
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1296
OMA	1	1.010	-	-		QHG51929
OrthoDB	1	1.010	-	-		D438205at33208
OrthoFinder	1	1.000	-	-		FOG0005543
OrthoInspector	1	1.000	-	-		otm25887
orthoMCL	1	0.900	-	-		OOG6_104067
Panther	1	1.100	-	-	O	PTHR47330
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3961
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910