DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hfp and cocoon

DIOPT Version :9

Sequence 1:	NP_525123.2	Gene:	hfp / 38173	FlyBaseID:	FBgn0028577	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001261874.1	Gene:	cocoon / 39665	FlyBaseID:	FBgn0036496	Length:	318	Species:	Drosophila melanogaster

Alignment Length:	155	Identity:	31/155 - (20%)
Similarity:	60/155 - (38%)	Gaps:	12/155 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 VLMKQTLAHQQQQLATQRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPIKSINMSWD 164
            |..|:.....:..|.....:.:|.:|......:.|..:|:...|..:|..|..:|.:....:..|
  Fly    77 VFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKD 141

  Fly   165 PITQKHKGFAFVEYEIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVIDEVQEEAKSFNRI 229
            ..:...|||.||.:...:.....|.:.:.  :.||..:|..|::.....      ||..|    :
  Fly   142 TRSGHSKGFGFVRFGSYDVQMHVLSKRHS--IDGRWCEVKVPASRGMGN------QEPGK----V 194

  Fly   230 YVASIHPDLSEEDIKSVFEAFGPIL 254
            :|.....|:..:|::..|..||.::
  Fly   195 FVGRCTEDIEADDLREYFSKFGEVI 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hfp	NP_525123.2	half-pint	10..637	CDD:130706	31/155 (20%)
		RRM1_PUF60	130..205	CDD:240816	16/74 (22%)
		RRM2_PUF60	227..303	CDD:240817	6/28 (21%)
		RRM3_UHM_PUF60	536..636	CDD:241092
cocoon	NP_001261874.1	RRM1_TDP43	108..184	CDD:240767	17/77 (22%)
cocoon	NP_001261874.1	RRM2_TDP43	193..262	CDD:240768	7/31 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439569
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840