DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hfp and TBPH

DIOPT Version :9

Sequence 1:	NP_525123.2	Gene:	hfp / 38173	FlyBaseID:	FBgn0028577	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001163280.1	Gene:	TBPH / 37781	FlyBaseID:	FBgn0025790	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	154	Identity:	30/154 - (19%)
Similarity:	61/154 - (39%)	Gaps:	12/154 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 VLMKQTLAHQQQQLATQRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPIKSINMSWD 164
            |..|:........|.....:.:|.:.......:.|..:.::..|:::|..|..:|.:....:..|
  Fly    77 VFPKENKRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKD 141

  Fly   165 PITQKHKGFAFVEYEIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVIDEVQEEAKSFNRI 229
            ..:.:.|||.||.:...:.....|  .|..|:.||..:|..|::.....||.          .::
  Fly   142 TKSGQSKGFGFVRFGSYDAQMRVL--TNRHLIDGRWCEVKVPNSKGMGHQVP----------CKV 194

  Fly   230 YVASIHPDLSEEDIKSVFEAFGPI 253
            :|.....|::.:|::..|..||.:
  Fly   195 FVGRCTEDINSDDLREYFSKFGEV 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hfp	NP_525123.2	half-pint	10..637	CDD:130706	30/154 (19%)
		RRM1_PUF60	130..205	CDD:240816	17/74 (23%)
		RRM2_PUF60	227..303	CDD:240817	6/27 (22%)
		RRM3_UHM_PUF60	536..636	CDD:241092
TBPH	NP_001163280.1	RRM1_TDP43	108..184	CDD:240767	18/77 (23%)
TBPH	NP_001163280.1	RRM2_TDP43	192..261	CDD:240768	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840