DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hfp and ZK616.1

DIOPT Version :9

Sequence 1:	NP_525123.2	Gene:	hfp / 38173	FlyBaseID:	FBgn0028577	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001379953.1	Gene:	ZK616.1 / 191358	WormBaseID:	WBGene00022771	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	296	Identity:	70/296 - (23%)
Similarity:	112/296 - (37%)	Gaps:	82/296 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RVYVGSISFELKEDTIRVAFT----PFGPIKSINMSWDPI---TQKHKGFAFVEYEIPEGAQLAL 188
            |:|||..|..|..:.||...|    ||      .:|.|.:   ::||:|||||:......|.:.|
Worm    10 RLYVGGFSTNLSSEQIRNLITQLAAPF------EVSIDIVENGSRKHRGFAFVQCRSLAEANVLL 68

  Fly   189 EQMNGALMGGRNIKVGRPSNMPQ-AQQVIDEVQEEAKSFNRIYVASIHPDLSEEDIKSVFEAFGP 252
            .:.:|..     .||......|: |:.|:..:       :.::|..|..|:.:.::   ::|||.
Worm    69 AKFSGLF-----TKVNFAKKEPKPAENVMSNI-------SNVFVRGISRDMPDTEL---YQAFGG 118

  Fly   253 I----LYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGGQLL--------RVGRSIT 305
            |    :.|        |...||||:.:..:....:.|..|:...|.|:|:        .|||...
Worm   119 ITDGVVQC--------HVADGYGFVLFDTRANAQKKIVEMDGKTLNGKLISVSWARPDTVGRKRK 175

  Fly   306 PPNALACPTTNSTMPTAAAVAAAAATAKIQALDAVASNAVLGLSQNTPVMAAGAVVTKVGAMPVV 370
            .|.:...||.:||                          .||||.   ::....:.:.:..:|..
Worm   176 RPMSEESPTPSST--------------------------DLGLSS---LLKRPVIPSHLFQLPPQ 211

  Fly   371 SAATSAAALHPALAQAAPALLPPGIFQAPTPVAPSL 406
            .|.....:|.|.|..:.|.|.|    |.|....|.|
Worm   212 PAQILQPSLIPFLNPSFPLLFP----QNPLLAQPDL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hfp	NP_525123.2	half-pint	10..637	CDD:130706	70/296 (24%)
		RRM1_PUF60	130..205	CDD:240816	25/80 (31%)
		RRM2_PUF60	227..303	CDD:240817	20/87 (23%)
		RRM3_UHM_PUF60	536..636	CDD:241092
ZK616.1	NP_001379953.1	hnRNP-R-Q	<2..>220	CDD:273732	60/267 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000