Protein Alignment KLK2 and alphaTry

DIOPT Version :9

• Sequence 1: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 86/270 - (31%)
• Similarity: 123/270 - (45%)
• Gaps: 41/270 - (15%)

Human     4 LVLSIALSVGCT---GAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
            |:.::..::|.|   |.:|.:..|||||......|.|||:::...|...|||.:.....::||||
  Fly     7 LLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAH 71

Human    66 CL----------KKNSQVWLGRHNLFEPEDTGQRVPVSHSFP-HPLYNMSLLKHQSLRPDEDSSH 119
            ||          :..|..|          .:|..|....||. |..||.:.:           .:
  Fly    72 CLQSVSASVLQVRAGSTYW----------SSGGVVAKVSSFKNHEGYNANTM-----------VN 115

Human   120 DLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC 184
            |:.::|||.....:..:|.:.|.|..||.|.:...||||:........|..||.|:::::|...|
  Fly   116 DIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQC 180

Human   185 ARA---YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKV 246
            |.:   |..::...|:||.  ..|||.|.||||||||..|||.|:.||| ..||....|.||..|
  Fly   181 ASSTYGYGSQIRNTMICAA--ASGKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADV 242

Human   247 VHYRKWIKDT 256
            ...|.|:..|
  Fly   243 AVLRSWVVST 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	79/244 (32%)
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	79/242 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5403
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.860