DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stet and PCP1

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_011615.1	Gene:	PCP1 / 852993	SGDID:	S000003333	Length:	346	Species:	Saccharomyces cerevisiae

Alignment Length:	203	Identity:	53/203 - (26%)
Similarity:	80/203 - (39%)	Gaps:	62/203 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 WRFL-FYMVL-----------------HAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGV 315
            |||| .||:|                 |..:.|||.|:.....||..|..:.|::....:|.:..
Yeast   166 WRFLQKYMLLQKDYVTSKISIIGSAFSHQEFWHLGMNMLALWSFGTSLATMLGASNFFSLYMNSA 230

  Fly   316 LAGSLGT---------SIFDPDVFLVGASG------GVYALLAAHLANVLLNYHQMRYGVIKLLH 365
            :||||.:         :|..|.   :||||      |.::.|..| |.:||....:..|
Yeast   231 IAGSLFSLWYPKLARLAIVGPS---LGASGALFGVLGCFSYLFPH-AKILLFVFPVPGG------ 285

  Fly   366 ILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSF 430
              .:|:|....|..|  ||..|:.||               ..|.|||.|::.|:..|..:.|:.
Yeast   286 --AWVAFLASVAWNA--AGCALRWGS---------------FDYAAHLGGSMMGVLYGWYISKAV 331

  Fly   431 EQKLHEQL 438
            |::...:|
Yeast   332 EKQRQRRL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	50/191 (26%)
PCP1	NP_011615.1	Rhomboid	186..329	CDD:396315	43/171 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810