DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stet and rhbdf1a

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_005164392.1	Gene:	rhbdf1a / 798402	ZFINID:	ZDB-GENE-040704-75	Length:	893	Species:	Danio rerio

Alignment Length:	202	Identity:	53/202 - (26%)
Similarity:	88/202 - (43%)	Gaps:	42/202 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 PDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFD 326
            ||:.:.:|..||   ||||.||...:|..|:.....||.:.|..||:.||....:.|:|.::||.
Zfish   688 PDQFYRLWLSLF---LHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLASAIFL 749

  Fly   327 PDVFLVGASGGVYALLAAHLANVLLNYH---QMRYGVIKLLHILVFVSFDFGFAIYARYAGDELQ 388
            |....||.:|..:.:||.....::.::.   |......|||.:::|: |.||...:
Zfish   750 PYRAEVGPAGSQFGILACLFVELIQSWQILAQPWRAFTKLLCVVLFL-FAFGLLPW--------- 804

  Fly   389 LGSSSEFLAIDQAETAGAVSYVAHLAGAIAG--LTIGLLVLKSF-----EQKLHEQLLWWIA-LG 445
                              :...||::|.|:|  |:...|...||     .:|..:.:::.:. ||
Zfish   805 ------------------IDNFAHISGFISGFFLSFAFLPYISFGRLDMYRKRCQIIIFLVVFLG 851

  Fly   446 TYLALVV 452
            .:..|||
Zfish   852 LFAGLVV 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	45/170 (26%)
rhbdf1a	XP_005164392.1	Rhomboid_SP	130..347	CDD:289371
		Rhomboid	685..826	CDD:279958	44/168 (26%)
		DUF805	<792..864	CDD:294752	19/95 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820