DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stet and rhbdf1b

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_021328201.1	Gene:	rhbdf1b / 563403	ZFINID:	ZDB-GENE-130531-6	Length:	894	Species:	Danio rerio

Alignment Length:	209	Identity:	48/209 - (22%)
Similarity:	85/209 - (40%)	Gaps:	42/209 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 PDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFD 326
            ||:.:.:|..||   ||||.||...:|..|:.....||.:.|..||:.||....:.|:|.::||.
Zfish   689 PDQFYRLWLSLF---LHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLASAIFL 750

  Fly   327 PDVFLVGASGGVYALLAAHLANVLLNYHQMR---YGVIKLLHILVFVSFDFGFAIYARYAGDELQ 388
            |....||.:|..:.:||.....:..::..:.   ....||..:::|: |.||...:
Zfish   751 PYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFTKLSCVVLFL-FAFGLLPW--------- 805

  Fly   389 LGSSSEFLAIDQAETAGAVSYVAHLAGAIAG--LTIGLLVLKSF------EQKLHEQLLWWIALG 445
                              :...||:.|.::|  |:...|...||      .::|...:...:.:|
Zfish   806 ------------------IDNFAHICGFVSGFFLSFAFLPYISFGRMDMYRKRLQILVALTLFVG 852

  Fly   446 TYLALVVFAIAFNI 459
            .:.:.||....:.:
Zfish   853 IFSSFVVLFYVYPV 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	42/170 (25%)
rhbdf1b	XP_021328201.1	Rhomboid_SP	130..348	CDD:315299
rhbdf1b	XP_021328201.1	Rhomboid	686..829	CDD:307698	42/170 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920