DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stet and rhbdl2

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001016521.1	Gene:	rhbdl2 / 549275	XenbaseID:	XB-GENE-992044	Length:	290	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	114/276 - (41%)
Similarity:	163/276 - (59%)	Gaps:	31/276 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 KMVHAVAMEILPEERDRKYYADRYTCCPPPFFIILVTLVELGFFVYHSV-------VTGEAAPRG 250
            |:...::..|||..: |..|.:|..|.|||.|||.|::.||..|:|::|       :|.:..
Frog    31 KIHETISNWILPTNQ-RDTYLERANCLPPPIFIISVSIAELAVFIYYAVWMPQKQWITLDTG--- 91

  Fly   251 PIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGV 315
              ..:|.||||||||.|.|||:.||::|||..|:..|:|:||:.|:|||:||...||..:|.:||
Frog    92 --VWNSPFIYRPDKREEAWRFISYMMVHAGVQHIIGNLALQLLLGIPLELVHKGHRIGLVYLAGV 154

  Fly   316 LAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQM--RYGVIKLLHILVFVSFDFGFAI 378
            :.|||.:|:||..:.|||||||||||:..:..|||:|:..|  .:|:.::|.|:..|..|.|||:
Frog   155 IGGSLASSVFDSGLALVGASGGVYALIGGYFMNVLVNFKDMIPLFGIFRILVIITIVGTDVGFAL 219

  Fly   379 YARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIA 443
            |.||...                ||...||:|||.||.:||::||..|...|::.|.:...:||.
Frog   220 YRRYISH----------------ETGQKVSFVAHFAGGLAGMSIGYTVFSCFDKNLIKDPRFWIC 268

  Fly   444 LGTYLALVVFAIAFNI 459
            :..|.|.|:||:.|||
Frog   269 IAAYAAFVIFAVLFNI 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	76/167 (46%)
rhbdl2	NP_001016521.1	Rhomboid	103..252	CDD:366759	73/164 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I4515
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45840
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110